{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:28:49Z","timestamp":1747150129707,"version":"3.40.5"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T00:00:00Z","timestamp":1594252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Binzhou Central Hospital"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Kaohsiung J of Med Scie"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>It has been reported microRNA\u2010301b (miR\u2010301b) was involved in the tumorigenesis of some cancers, but it has not been investigated in cervical carcinoma yet. In this study, miR\u2010301b was found significantly upregulated in cervical carcinoma, and patients with high miR\u2010301b expression had a shorter overall survival. When miR\u2010301b was knocked down in cervical carcinoma cells, the cell growth could be significantly abolished. Our further studies showed miR\u2010301b targeted RNF38, and inhibited its expression in cervical carcinoma cells. Moreover, RNF38 was found downregulated in cervical carcinoma, and miR\u2010301b expression in cervical tissues was found negatively correlated with RNF38 expression. In addition, overexpression of RNF38 significantly inhibited cervical carcinoma cell growth, but overexpression of miR\u2010301b suppressed RNF38\u2010induced cell growth inhibition in cervical carcinoma. Collectively, this study suggested miR\u2010301b could be a novel target for cervical carcinoma treatment.<\/jats:p>","DOI":"10.1002\/kjm2.12273","type":"journal-article","created":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T10:11:18Z","timestamp":1594289478000},"page":"878-884","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Inhibiting <scp>microRNA<\/scp>\u2010301b suppresses cell growth and targets <scp>RNF38<\/scp> in cervical carcinoma"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2243-426X","authenticated-orcid":false,"given":"Wen\u2010Ling","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Obstetrics Binzhou Central Hospital  Binzhou Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Binzhou Central Hospital  Binzhou Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian\u2010Lin","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Emergency Binzhou Central Hospital  Binzhou Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue\u2010Mei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Binzhou Central Hospital  Binzhou Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan\u2010Ying","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Binzhou Central Hospital  Binzhou Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l1207"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S224525"},{"key":"e_1_2_8_4_1","first-page":"493","article-title":"Prevalence of high\u2010risk HPV and its distribution in cervical precancerous lesions among 35\u201064\u2009years old women who received cervical cancer screening in Beijing","volume":"52","author":"Shen J","year":"2018","journal-title":"Zhonghua Yu Fang Yi Xue Za Zhi"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.00976"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-5851.92808"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S195098"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.11543"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.15190\/d.2016.4"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1672-0229(08)60044-3"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/kjm2.12057"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-019-03317-9"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-019-1113-3"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S234828"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.5483\/BMBRep.2018.51.11.168"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-6990-6_9"},{"key":"e_1_2_8_17_1","first-page":"9277","article-title":"Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets","volume":"8","author":"Nagy \u00c1","year":"2018","journal-title":"Sci Rep"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2019.152667"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2014.2243"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.896832"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753425919840702"}],"container-title":["The Kaohsiung Journal of Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fkjm2.12273","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/kjm2.12273","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/kjm2.12273","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/kjm2.12273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T02:19:41Z","timestamp":1693880381000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/kjm2.12273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,9]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1002\/kjm2.12273"],"URL":"https:\/\/doi.org\/10.1002\/kjm2.12273","archive":["Portico"],"relation":{},"ISSN":["1607-551X","2410-8650"],"issn-type":[{"type":"print","value":"1607-551X"},{"type":"electronic","value":"2410-8650"}],"subject":[],"published":{"date-parts":[[2020,7,9]]},"assertion":[{"value":"2020-04-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}