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In addition, miR\u201010a\u20105p restrained the viability, colony formation, migration ability and invasiveness of OC cells. We further ascertained Homeobox A1 (HOXA1) was a downstream gene of miR\u201010a\u20105p. Furthermore, HOXA1 was distinctly upregulated in OC samples. Finally, upregulation of HOXA1 abolished the suppressive effects of miR\u201010a\u20105p on OC cells. These observations suggested that miR\u201010a\u20105p suppressed the aggressive phenotypes of OC cells via regulating HOXA1.<\/jats:p>","DOI":"10.1002\/kjm2.12335","type":"journal-article","created":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T11:35:53Z","timestamp":1608291353000},"page":"276-285","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["<scp>MiR<\/scp>\u201010a\u20105p restrains the aggressive phenotypes of ovarian cancer cells by inhibiting <scp>HOXA1<\/scp>"],"prefix":"10.1002","volume":"37","author":[{"given":"Li\u2010Jun","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Gynaecology Rongcheng People's Hospital  Weihai Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Yan","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Gynaecology Rongcheng People's Hospital  Weihai Shandong 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