{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T11:02:35Z","timestamp":1756810955787,"version":"3.40.5"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T00:00:00Z","timestamp":1698364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004694","name":"Kaohsiung Medical University","doi-asserted-by":"publisher","award":["KMUH109\u20109R05","MOST 111\u20102314\u2010B\u2010037\u2010069\u2010MY2"],"award-info":[{"award-number":["KMUH109\u20109R05","MOST 111\u20102314\u2010B\u2010037\u2010069\u2010MY2"]}],"id":[{"id":"10.13039\/501100004694","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011645","name":"KMUH","doi-asserted-by":"publisher","award":["KMUH110\u20100M03","KMUH110\u20100M06","KMHK\u2010DK(C)111004","KMUH\u2010DK(\u6574)109005~1","KMUH\u2010DK(B)111002\u20101","KMHK\u2010DK(C)111006"],"award-info":[{"award-number":["KMUH110\u20100M03","KMUH110\u20100M06","KMHK\u2010DK(C)111004","KMUH\u2010DK(\u6574)109005~1","KMUH\u2010DK(B)111002\u20101","KMHK\u2010DK(C)111006"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008903","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["MOHW111\u2010TDU\u2010B\u2010221\u2010014007"],"award-info":[{"award-number":["MOHW111\u2010TDU\u2010B\u2010221\u2010014007"]}],"id":[{"id":"10.13039\/100008903","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Kaohsiung J of Med Scie"],"published-print":{"date-parts":[[2024,2]]},"abstract":"Abstract<\/jats:title>Elevated serum gamma\u2010glutamyl transferase (GGT) levels are associated with chronic hepatitis B (CHB)\u2010related hepatocellular carcinoma. However, their role in predicting mortality in patients with CHB treated with nucleotide\/nucleoside analogs (NAs) remains elusive. Altogether, 2843 patients with CHB treated with NAs were recruited from a multinational cohort. Serum GGT levels before and 6\u2009months (Month\u20106) after initiating NAs were measured to explore their association with all\u2010cause, liver\u2010related, and non\u2010liver\u2010related mortality. The annual incidence of all\u2010cause mortality was 0.9\/100 person\u2010years over a follow\u2010up period of 17,436.3 person\u2010years. Compared with patients who survived, those who died had a significantly higher pretreatment (89.3 vs. 67.4\u2009U\/L, p<\/jats:italic>\u2009=\u20090.002) and Month\u20106\u2010GGT levels (62.1 vs. 38.4\u2009U\/L, p<\/jats:italic>\u2009<\u20090.001). The factors associated with all\u2010cause mortality included cirrhosis (hazard ratio [HR]\/95% confidence interval [CI]: 2.66\/1.92\u20133.70, p<\/jats:italic>\u2009<\u20090.001), pretreatment GGT levels (HR\/CI: 1.004\/1.003\u20131.006, p<\/jats:italic>\u2009<\u20090.001), alanine aminotransferase level (HR\/CI: 0.996\/0.994\u20130.998, p<\/jats:italic>\u2009=\u20090.001), and age (HR\/CI: 1.06\/1.04\u20131.07, p<\/jats:italic>\u2009<\u20090.001). Regarding liver\u2010related mortality, the independent factors included cirrhosis (HR\/CI: 4.36\/2.79\u20136.89, p<\/jats:italic>\u2009<\u20090.001), pretreatment GGT levels (HR\/CI: 1.006\/1.004\u20131.008, p<\/jats:italic>\u2009<\u20090.001), alanine aminotransferase level (HR\/CI: 0.993\/0.990\u20130.997, p<\/jats:italic>\u2009=\u20090.001), age (HR\/CI: 1.03\/1.01\u20131.05, p<\/jats:italic>\u2009<\u20090.001), and fatty liver disease (HR\/CI: 0.30\/0.15\u20130.59, p<\/jats:italic>\u2009=\u20090.001). Pretreatment GGT levels were also independently predictive of non\u2010liver\u2010related mortality (HR\/CI: 1.003\/1.000\u20131.005, p<\/jats:italic>\u2009=\u20090.03). The results remained consistent after excluding the patients with a history of alcohol use. A dose\u2010dependent manner of <25, 25\u201375, and >75 percentile of pretreatment GGT levels was observed with respect to the all\u2010cause mortality (trend p<\/jats:italic>\u2009<\u20090.001). Pretreatment serum GGT levels predicted all\u2010cause, liver\u2010related, and non\u2010liver\u2010related mortality in patients with CHB treated with NAs.<\/jats:p>","DOI":"10.1002\/kjm2.12771","type":"journal-article","created":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T07:29:05Z","timestamp":1698391745000},"page":"188-197","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pretreatment gamma\u2010glutamyl transferase predicts mortality in patients with chronic hepatitis B treated with nucleotide\/nucleoside analogs"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2961-130X","authenticated-orcid":false,"given":"Tyng\u2010Yuan","family":"Jang","sequence":"first","affiliation":[{"name":"Ph.D. Program in Environmental and Occupational Medicine, College of Medicine Kaohsiung Medical University and National Health Research Institutes Kaohsiung Taiwan"},{"name":"Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po\u2010Cheng","family":"Liang","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae Won","family":"Jun","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hanyang University Hospital, Hanyang University College of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jang Han","family":"Jung","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine Severance Hospital, Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidenori","family":"Toyoda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Ogaki Municipal Hospital Gifu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5293-2841","authenticated-orcid":false,"given":"Chih\u2010Wen","family":"Wang","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Man\u2010Fung","family":"Yuen","sequence":"additional","affiliation":[{"name":"Department of Medicine School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong Hong Kong Hong Kong"},{"name":"State Key Laboratory of Liver Research The University of Hong Kong Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ka Shing","family":"Cheung","sequence":"additional","affiliation":[{"name":"Department of Medicine School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Yasuda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Ogaki Municipal Hospital Gifu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Eun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hallym University Sacred Heart Hospital, Hallym University College of Medicine Anyang South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eileen L.","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hanyang University Hospital, Hanyang University College of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihyun","family":"An","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hanyang University College of Medicine, Hanyang University Guri Hospital Guri South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Enomoto","sequence":"additional","affiliation":[{"name":"Department of Hepatology Graduate School of Medicine, Osaka Metropolitan University Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ritsuzo","family":"Kozuka","sequence":"additional","affiliation":[{"name":"Department of Hepatology Graduate School of Medicine, Osaka Metropolitan University Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Chuma","sequence":"additional","affiliation":[{"name":"Gastroenterological Center Yokohama City University Medical Center Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akito","family":"Nozaki","sequence":"additional","affiliation":[{"name":"Gastroenterological Center Yokohama City University Medical Center Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Saiseikai Niigata Hospital Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsunamasa","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology St. Marianna University School of Medicine Kawasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Atsukawa","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Nippon Medical School Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taeang","family":"Arai","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Nippon Medical School Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Korenobu","family":"Hayama","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Nippon Medical School Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Ishigami","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Hepatology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Kyun","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiichi","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine Kyushu University Kyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyoung Su","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae\u2010Jun","family":"Shim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kyung Hee University Hospital, Kyung Hee University School of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruki","family":"Uojima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Internal Medicine, Kitasato University School of Medicine Sagamihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soung Won","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Soonchunhyang University Hospital, Soonchunhyang University College of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Bong","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Nowon Eulji Medical Center, Eulji University College of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Takaguchi","sequence":"additional","affiliation":[{"name":"Department of Hepatology Kagawa Prefectural Central Hospital Kagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Senoh","sequence":"additional","affiliation":[{"name":"Department of Hepatology Kagawa Prefectural Central Hospital Kagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Buti","sequence":"additional","affiliation":[{"name":"Liver Unit Hospital Universitari Vall d'Hebron and CIBEREHD del Instituto Carlos III Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Vargas\u2010Accarino","sequence":"additional","affiliation":[{"name":"Liver Unit Hospital Universitari Vall d'Hebron and CIBEREHD del Instituto Carlos III Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Abe","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Shinmatsudo Central General Hospital Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Liver Center Saga University Hospital Saga Japan"},{"name":"Division of Metabolism and Endocrinology, Faculty of Medicine Saga University Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Inoue","sequence":"additional","affiliation":[{"name":"Liver Center Saga University Hospital Saga Japan"},{"name":"Division of Metabolism and Endocrinology, Faculty of Medicine Saga University Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jee\u2010Fu","family":"Huang","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital Kaohsiung Taiwan"},{"name":"Faculty of Internal Medicine and Hepatitis Research Center, School of Medicine, College of Medicine, and Center for Cancer Research and Liquid Biopsy Kaohsiung Medical University Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan\u2010Long","family":"Chuang","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital Kaohsiung Taiwan"},{"name":"Faculty of Internal Medicine and Hepatitis Research Center, School of Medicine, College of Medicine, and Center for Cancer Research and Liquid Biopsy Kaohsiung Medical University Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3728-7618","authenticated-orcid":false,"given":"Ming\u2010Lun","family":"Yeh","sequence":"additional","affiliation":[{"name":"Kaohsiung Medical University Hospital Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia\u2010Yen","family":"Dai","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital Kaohsiung Taiwan"},{"name":"Faculty of Internal Medicine and Hepatitis Research Center, School of Medicine, College of Medicine, and Center for Cancer Research and Liquid Biopsy Kaohsiung Medical University Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3367-068X","authenticated-orcid":false,"given":"Chung\u2010Feng","family":"Huang","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital Kaohsiung Taiwan"},{"name":"Faculty of Internal Medicine and Hepatitis Research Center, School of Medicine, College of Medicine, and Center for Cancer Research and Liquid Biopsy Kaohsiung Medical University Kaohsiung Taiwan"},{"name":"Translational Medicine College of Medicine, Kaohsiung Medical University, Kaohsiung, and Academia Sinica Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6275-4989","authenticated-orcid":false,"given":"Mindie H.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine Stanford University Medical Center Palo Alto California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8145-1900","authenticated-orcid":false,"given":"Ming\u2010Lung","family":"Yu","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital Kaohsiung Taiwan"},{"name":"Faculty of Internal Medicine and Hepatitis Research Center, School of Medicine, College of Medicine, and Center for Cancer Research and Liquid Biopsy Kaohsiung Medical University Kaohsiung Taiwan"},{"name":"School of Medicine, College of Medicine, National Sun Yat\u2010Sen University Kaohsiung Taiwan"},{"name":"Division of Hepato\u2010Gastroenterology, Department of Internal Medicine Kaohsiung Chang Gung Memorial Hospital Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,10,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(22)00124-8"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy598"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15803"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-027696"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3110-0"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14801"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00046-19","article-title":"Hepatitis B virus: advances in prevention, diagnosis, and therapy","volume":"33","author":"Nguyen MH","year":"2020","journal-title":"Clin Microbiol Rev"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/20014091084227"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13221"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/818570"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22320"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.15085"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.02.022"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-015-9675-4"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2018.11.008"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.12269"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2019.1002"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20506"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.35354"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-018-0055-0"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.213553"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.10.031"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0609.2002.01636.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.02.021"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-6686"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2022.101435"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2014.3693"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i34.9957"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-021-02214-1"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e328354044a"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-020-01369-x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2022.155222"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2019.02.002"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa739"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2015.240424"}],"container-title":["The Kaohsiung Journal of Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/kjm2.12771","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T14:35:54Z","timestamp":1706884554000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/kjm2.12771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,27]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1002\/kjm2.12771"],"URL":"https:\/\/doi.org\/10.1002\/kjm2.12771","archive":["Portico"],"relation":{},"ISSN":["1607-551X","2410-8650"],"issn-type":[{"type":"print","value":"1607-551X"},{"type":"electronic","value":"2410-8650"}],"subject":[],"published":{"date-parts":[[2023,10,27]]},"assertion":[{"value":"2023-08-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}