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The current study aimed to facilitate HCV treatment uptake by implementing an integrated outreach care model. Multidisciplinary outreach screening followed by HCV reflex testing and onsite treatment for schizophrenia patients was accomplished through the coordination of nongovernmental organizations, remote specialists, and local care providers. The objective was microelimination effectiveness, defined as the multiplication of the rates of anti\u2010HCV antibodies screening, accurate HCV RNA diagnosis, treatment allocation, treatment completion, and sustained virological response (SVR12; no detectable HCV RNA throughout 12\u2009weeks in the post\u2010treatment follow\u2010up period). A total of 1478 of the 2300 (64.3%) psychiatric patients received HCV mass screening. Seventy\u2010three (4.9%) individuals were seropositive for anti\u2010HCV antibodies. Of the 73 anti\u2010HCV seropositive patients, all (100%) received HCV reflex testing, and 29 (37.7%) patients had HCV viremia. Eight patients (34.8%) had advanced liver disease, including 3 with liver cirrhosis and 2 with newly diagnosed hepatocellular carcinoma. Twenty\u2010three of the 24 (95.8%) patients who stayed in the healthcare system received and completed 8\u2009weeks of glecaprevir\/pibrentasvir treatment and post\u2010treatment follow\u2010up without significant DDIs or adverse events. The SVR12 rate was 100%. The microelimination effectiveness in the current study was 61.6%. Individuals with serious mental illness are underserved and suffer from diagnostic delays. This patient\u2010centered and integrated outreach program facilitated HCV care in this marginalized population.<\/jats:p>","DOI":"10.1002\/kjm2.12780","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T11:16:08Z","timestamp":1699528568000},"page":"86-93","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Patient\u2010centered and integrated outreach care for chronic hepatitis <scp>C<\/scp> patients with serious mental illness in <scp>Taiwan<\/scp>"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3367-068X","authenticated-orcid":false,"given":"Chung\u2010Feng","family":"Huang","sequence":"first","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital  Kaohsiung Taiwan"},{"name":"Ph.D. Program in Translational Medicine, College of Medicine Kaohsiung Medical University  Kaohsiung 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