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However, various factors can disrupt the development of the gut microbiota, leading to a condition known as dysbiosis, particularly in preterm infants. Current studies involving adults have suggested that the gut microbiota not only influences the gut but also has multidimensional effects on remote organs; these pathways are often referred to as the gut\u2013organ axis. Imbalance of the gut microbiota may lead to the development of multiple diseases. Recent studies have revealed that gut dysbiosis in preterm infants may cause several acute morbidities\u2014such as necrotizing enterocolitis, late\u2010onset sepsis, bronchopulmonary dysplasia, and retinopathy of prematurity\u2014and it may also influence long\u2010term outcomes including neurodevelopment and somatic growth. This review mainly presents the existing evidence regarding the relationships between the gut microbiota and these morbidities in preterm infants and explores the role of the gut\u2013organ axis in these morbidities. This paper thus offers insights into the future perspectives on microbiota interventions for promoting the health of preterm infants.<\/jats:p>","DOI":"10.1002\/kjm2.12878","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T07:44:10Z","timestamp":1722239050000},"page":"780-788","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The impact of gut microbiota on morbidities in preterm infants"],"prefix":"10.1002","volume":"40","author":[{"given":"Mei\u2010Yin","family":"Lai","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, School of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin\u2010Hsi","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chang Gung Memorial Hospital, School of Medicine Chang Gung 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