{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T03:57:16Z","timestamp":1770436636292,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUH113\u20103R42"],"award-info":[{"award-number":["KMUH113\u20103R42"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Kaohsiung J of Med Scie"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Anomalous pulmonary venous connection (APVC), including total (TAPVC) and partial (PAPVC) forms, is a congenital heart defect with abnormal pulmonary vein drainage; and while surgical repair has improved survival, its long\u2010term impact on cardiopulmonary function remains unclear. This retrospective study evaluated exercise capacity and pulmonary function in 26 pediatric APVC patients (17 TAPVC, 9 PAPVC) using cardiopulmonary exercise testing (CPET) and compared them with 63 age\u2010matched healthy controls. Patients with complex defects or significant comorbidities were excluded. Results showed significantly lower anaerobic threshold VO\n                    <jats:sub>2<\/jats:sub>\n                    (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.03), peak VO\n                    <jats:sub>2<\/jats:sub>\n                    (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) and peak heart rate (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.02) in the APVC group, indicating impaired exercise capacity; though no differences were found between TAPVC and PAPVC subgroups. Despite preserved resting lung function, these findings suggest that children with repaired APVC experience persistent exercise limitations, underscoring the importance of routine functional assessment and potential rehabilitation, with further studies needed to clarify underlying mechanisms and guide long\u2010term care.\n                  <\/jats:p>","DOI":"10.1002\/kjm2.70101","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T10:19:14Z","timestamp":1756894754000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exercise Capacity and Pulmonary Function in Pediatric Patients With Anomalous Pulmonary Venous Connection Post\u2010Surgical Repair: A Retrospective Analysis"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6850-3111","authenticated-orcid":false,"given":"Yen\u2010Hsien","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Pediatrics Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen\u2010Sen","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng\u2010Hui","family":"Tuan","sequence":"additional","affiliation":[{"name":"Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University  Tainan City Taiwan"},{"name":"Department of Rehabilitation Medicine Cishan Hospital, Ministry of Health and Welfare  Kaohsiung Taiwan"},{"name":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, College of Medicine Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi\u2010Ching","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I\u2010Ching","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi\u2010Cheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tang\u2010Hsu","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih\u2010Hsing","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ko\u2010Long","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, College of Medicine Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong\u2010Hau","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"School of Medicine, College of Medicine Kaohsiung Medical University  Kaohsiung 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