{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T11:09:25Z","timestamp":1778324965390,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Kaohsiung J of Med Scie"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The age\u2010related decline in accommodative function after the age of 50\u2009years corresponds with an increasing incidence of primary angle\u2010closure disease (PACD); however, the interaction between this decline and PACD remains unexamined. Additionally, refractive error\u2010accommodation associations in elderly individuals, which are critical for PACD pathophysiology, remain unclear, despite a prior pediatric focus. This study evaluated visual functions (including binocular vision, vergence function, and accommodation function) in patients diagnosed with PACD. A total of 51 patients (102 eyes) were included in this prospective study. The subjects were categorized into the following three groups: primary angle\u2010closure\/primary angle\u2010closure glaucoma (PAC\/PACG), primary angle\u2010closure suspect (PACS), and a control group. Various parameters, including best\u2010corrected near visual acuity, refractive error, Worth's 4 Dot test results, stereoacuity, vergence facility, accommodative facility (AF), and amplitude of accommodation (AMP), were measured and compared across the groups. A negative correlation was noted between AMP and refractive error (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). After controlling for age and refractive error, no significant difference in AMP was detected; however, a statistically significant difference in AF was noted among the groups. PACS (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.002) and PAC\/PACG (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.048) emerged as independent predictors of strong AF compared with normal controls. No significant differences in best\u2010corrected near visual acuity, binocular vision, or vergence facility were observed between the groups. This research demonstrated that patients diagnosed with PACS and PAC\/PACG exhibited stronger AF compared with the control group. Furthermore, a negative correlation between AMP and refractive error was observed within the elderly population. This research characterizes the correlation between refractive status and accommodative function, while establishing a link between accommodative function and PACD. Future studies on PACD pathogenesis and clinical management should prioritize accommodative function as a key research focus.\n                  <\/jats:p>","DOI":"10.1002\/kjm2.70134","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T13:21:18Z","timestamp":1761916878000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Study of Accommodative Function and Binocular Vision in Patients With Primary Angle\u2010Closure Disease"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5053-4656","authenticated-orcid":false,"given":"Feng\u2010Rui","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi\u2010Qiao","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2889-5518","authenticated-orcid":false,"given":"Yao","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3349-986X","authenticated-orcid":false,"given":"Hui\u2010Juan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Peking University People's Hospital  Beijing China"},{"name":"Eye Diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry Peking University Health Science Center  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.2.238"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2021.10.003"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31469-1"},{"issue":"2","key":"e_1_2_7_5_1","article-title":"Prevalence and Risk Factors for Primary Angle\u2010Closure Disease Spectrum: The Colombian Glaucoma Study","volume":"32","author":"Mart\u00ednez\u2010Blanco A. 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