{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T05:24:58Z","timestamp":1787203498870,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Kaohsiung J of Med Scie"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The study aimed to investigate the efficacy of ultrasound\u2010guided intercostal nerve block (ICNB) with liposomal bupivacaine (LB) comparing ropivacaine\u2010dexamethasone (RD) for treating postherpetic neuralgia (PHN) in adult patients. A total of 108 patients were randomized 1:1 to receive ICNB with LB or ICNB with RD. The Visual Analogue Scale scores in the ICNB\u2010LB were significantly lower than those in the ICNB\u2010RD at 1 and 2\u2009weeks posttreatment (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). According to the EuroQol Health\u2010Related Quality of Life 5\u2010Dimension, 3\u2010Level questionnaire (EQ\u20105D\u20103L), lower proportions of patients reporting problems at 2\u2009weeks posttreatment were observed in the ICNB\u2010LB regarding the domains of pain\/discomfort (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.031), usual activities (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.027), and symptom of anxiety\/depression (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.038), versus the ICNB\u2010RD. The ICNB\u2010LB had less consumption of pregabalin than the ICNB\u2010RD at 1\u2009week (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.006) and 2\u2009weeks (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.013) posttreatment. The rate of pregabalin discontinuation was higher and the proportion of patients who required rescue analgesics was lower in ICNB\u2010LB versus ICNB\u2010RD up to Week 2 posttreatment. These results demonstrate LB provides an analgesic superiority through 2\u2009weeks without causing new safety concerns comparing with RD in ultrasound\u2010guided ICNB for treating adult patients with PHN.\n                  <\/jats:p>","DOI":"10.1002\/kjm2.70277","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T04:53:46Z","timestamp":1787201626000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of Ultrasound\u2010Guided Intercostal Nerve Block With Liposomal Bupivacaine for Treating Postherpetic Neuralgia in Adult Patients"],"prefix":"10.1002","author":[{"given":"Jin","family":"Li","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Kaihua County People's Hospital  Quzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4847-4040","authenticated-orcid":false,"given":"Xiang\u2010Yu","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Quzhou People\u2019s Hospital, The Quzhou Affiliated Hospital, Wenzhou Medical University  Quzhou China"},{"name":"Department of Anesthesiology The First Affiliated Hospital of Wenzhou Medical University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"issue":"1","key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/s41541-023-00757-0","article-title":"Healthy Ageing: Herpes Zoster Infection and the Role of Zoster Vaccination","volume":"8","author":"Curran D.","year":"2023","journal-title":"npj Vaccines"},{"issue":"10","key":"e_1_2_8_3_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jiph.2025.102868","article-title":"Global, Regional, and National Burden of Varicella\u2010Zoster Infections in Adults Aged 70\u2009Years and Older From 1997 to 2021: Findings From the Global Burden of Disease Study","volume":"18","author":"Yang C.","year":"2025","journal-title":"Journal of Infection and Public Health"},{"issue":"8","key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1093\/gerona\/glz085","article-title":"Zoster Vaccination in Older Adults: Efficacy and Public Health Implications","volume":"74","author":"McElhaney J. 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