{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:27:17Z","timestamp":1791822437345,"version":"4.3.4"},"reference-count":64,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T00:00:00Z","timestamp":1715731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study was to identify preoperative predictors for 1\u2010year posttotal knee arthroplasty (TKA) pain and pre\u2010 to post\u2010TKA pain difference in knee osteoarthritis (KOA) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From March 2018 to July 2023, this prospective longitudinal cohort study enrolled KOA patients awaiting TKA from four hospitals in Belgium and the Netherlands. Different biopsychosocial predictors were assessed preoperatively by questionnaires and physical examinations (input variables). The Knee injury and Osteoarthritis Outcome Score (KOOS) subscale pain was used to measure pain intensity. The absolute KOOS subscale pain score 1\u2010year post\u2010TKA and the difference score (\u0394KOOS\u2009=\u20091\u2010year postoperative\u2009\u2212\u2009preoperative) were used as primary outcome measures (output variables). Two multivariable linear regression analyses were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and twenty\u2010three\u00a0participants were included after multiple imputation. Worse absolute KOOS subscale pain scores 1\u2010year post\u2010TKA and negative or closer to zero \u0394KOOS subscale pain scores were predicted by self\u2010reported central sensitisation, lower KOA grade and preoperative satisfaction,\u00a0and higher glycated haemoglobin, number of pain locations\u00a0and personal control (adjusted <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.25). Additional predictors of negative or closer to zero \u0394KOOS subscale pain scores were being self\u2010employed, higher preoperative pain and function (adjusted <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.37).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study reports different biopsychosocial predictors for both outcomes that have filtered out other potential predictors and provide\u00a0value for future studies on developing risk assessment tools for the prediction of chronic TKA pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Protocol Registration<\/jats:title><jats:p>The protocol is registered at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link> (NCT05380648) on 13 May 2022.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>Level II.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ksa.12265","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T01:20:01Z","timestamp":1715822401000},"page":"201-219","source":"Crossref","is-referenced-by-count":7,"title":["Preoperative glycaemic control, number of pain locations, structural knee damage, self\u2010reported central sensitisation, satisfaction\u00a0and personal control are predictive of 1\u2010year postoperative pain, and change in pain from pre\u2010 to 1\u2010year posttotal knee arthroplasty"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3409-8504","authenticated-orcid":false,"given":"Sophie","family":"Vervullens","sequence":"first","affiliation":[{"name":"Research Group MOVANT, Department of Rehabilitation Sciences and Physiotherapy (REVAKI) University of Antwerp Wilrijk Belgium"},{"name":"Research School CAPHRI, Department of Rehabilitation Medicine Maastricht University Maastricht The Netherlands"},{"name":"Pain in Motion International Research Group (PiM), www.paininmotion.be Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0116-1346","authenticated-orcid":false,"given":"Lotte","family":"Meert","sequence":"additional","affiliation":[{"name":"Research Group MOVANT, Department of Rehabilitation Sciences and Physiotherapy (REVAKI) University of Antwerp Wilrijk Belgium"},{"name":"Research School CAPHRI, Department of Rehabilitation Medicine Maastricht University Maastricht The Netherlands"},{"name":"Pain in Motion International Research Group (PiM), www.paininmotion.be Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9503-366X","authenticated-orcid":false,"given":"Rob J. 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