{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:32:26Z","timestamp":1790443946994,"version":"4.1.0"},"reference-count":71,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T00:00:00Z","timestamp":1722816000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Patellofemoral pain, maltracking\u00a0and instability remain common and challenging complications after total knee arthroplasty. Controversy exists regarding the effect of kinematic alignment on the patellofemoral joint, as it generally leads to more femoral component valgus and internal rotation compared to mechanical alignment. The aim of this systematic review is\u00a0to thoroughly examine the influence of kinematic alignment on the third space.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic search of the Pubmed, Cochrane\u00a0and Web of Science databases was performed to screen for relevant articles published before 7 April 2024. This led to the final inclusion of 42 articles: 2 cadaveric, 9\u00a0radiographic, 12 computer simulation\u00a0and 19 clinical studies. The risk of bias was evaluated with the risk of bias in non\u2010randomised studies \u2010 of interventions tool as the lowest level of evidence of the included clinical studies was IV. The effects of kinematic alignment on patellar kinematics and kinetics, trochlear anatomy reconstruction\u00a0and patellofemoral complication rate were investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Kinematic alignment closely restores native patellar kinematics and kinetics,\u00a0better reproduces native trochlear anatomy than mechanical alignment and leads to a 0%\u201311.4% incidence of patellofemoral complications. A more valgus joint line of the distal femur can cause lateral trochlear undercoverage and a trochlear angle orientation medial to the quadriceps vector when applying kinematic alignment, both of which can be solved by using an adjusted design with a 20.5\u00b0 valgus trochlea.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Kinematic alignment appears to be a safe strategy for the patellofemoral joint in most knees, provided that certain precautions are taken to minimize the risk of complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level IV clinical studies, in vitro research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ksa.12401","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T05:14:00Z","timestamp":1722834840000},"page":"606-620","source":"Crossref","is-referenced-by-count":30,"title":["Kinematic alignment adequately restores trochlear anatomy, patellar kinematics and kinetics in total knee arthroplasty: A systematic review"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1239-9031","authenticated-orcid":false,"given":"Britt","family":"Ollivier","sequence":"first","affiliation":[{"name":"Department of Orthopaedics University Hospitals Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Luyckx","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery AZ Delta Roeselare Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Stragier","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University Hospitals Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilde","family":"Vandenneucker","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University Hospitals Leuven Leuven Belgium"},{"name":"Department of Development and Regeneration KU Leuven, University of Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-019-02499-z"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2016.01.040"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-016-4136-8"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-022-07206-w"},{"key":"e_1_2_11_6_1","unstructured":"Clarivate. 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