{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:53:04Z","timestamp":1790009584312,"version":"4.0.1"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T00:00:00Z","timestamp":1726617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["esskajournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study aimed to evaluate the long\u2010term outcomes of medial open wedge high tibial osteotomy (MOWHTO) as a treatment option for advanced medial compartment knee osteoarthritis (OA) Kellgren\u2013Lawrence (K\u2010L) III and IV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with severe medial compartment arthritis, who underwent MOWHTO with locking plate between 2003 and 2015, were retrospectively reviewed. A locking plate for the osteotomy was utilized. Preoperative and postoperative patients\u2019 evaluation was performed using the International Knee Documentation Committee Score (IKDC), the Oxford Knee Score (OKS), the Knee Injury Osteoarthritis Outcome Score (KOOS) and the Short Form\u201012 Score (SF\u201012). Standardized standing whole\u2010limb X\u2010rays were taken to evaluate the mechanical tibiofemoral angle (mTFA) and proximal medial tibial angle (PMTA), and the severity of OA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 32 patients, 35 knees (27 males, five females) of which 21 were classified as K\u2010L Grade III and 14 as K\u2010L Grade IV, and mean age 47.1\u2009\u00b1\u20099.17 years old, who were followed for 13.6 years (range 7\u201320 years), were included in the study. During the follow\u2010up period, three knees required conversion to total knee replacement (91.5% survival rate). All clinical outcome scores (KOOS, OKS, IKDC and SF\u201012) showed a significant improvement compared to preoperative status (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Preoperative mTFA and PMTA were significantly corrected immediately after surgery and retained this improvement at the last follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MOWHTO with a locking plate is an effective method to treat severe medial compartments. Clinical and radiological results are satisfactory and the survival rate is 91.5%, at a mean follow\u2010up of 13.6 years after the procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>Level IV.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ksa.12469","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T04:20:40Z","timestamp":1726633240000},"page":"1025-1032","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Medial open wedge high tibial osteotomy is a viable option in young patients with advanced arthritis in a long\u2010term follow\u2010up"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0368-0465","authenticated-orcid":false,"given":"Nifon K.","family":"Gkekas","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine University of Thessaly Mezourlo Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6832-0014","authenticated-orcid":false,"given":"George A.","family":"Komnos","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine University of Thessaly Mezourlo Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1377-7826","authenticated-orcid":false,"given":"Theodoros","family":"Mylonas","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine University of Thessaly Mezourlo Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6640-505X","authenticated-orcid":false,"given":"Georgios","family":"Chalatsis","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine University of Thessaly Mezourlo Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1811-6290","authenticated-orcid":false,"given":"Antonios A.","family":"Koutalos","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine University of Thessaly Mezourlo Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9494-6048","authenticated-orcid":false,"given":"Michael E.","family":"Hantes","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine University of Thessaly Mezourlo Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,18]]},"reference":[{"issue":"1","key":"e_1_2_12_2_1","first-page":"21","article-title":"High tibial valgus osteotomy for medial gonarthrosis: a 10\u2010 to 21\u2010year study","volume":"16","author":"Aglietti P.","year":"2003","journal-title":"The Journal of Knee Surgery"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-009-0889-8"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-023-07457-1"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.02.069"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2011.06.005"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30059-4"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513516577"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.10.025"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007760100003"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20632"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-022-07024-0"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2022.01.004"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1530\/EOR-22-0057"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-002-0446-z"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-017-4816-z"},{"issue":"3","key":"e_1_2_12_17_1","first-page":"241","article-title":"[A 20\u2010year follow\u2010up study of internal gonarthrosis after tibial valgus osteotomy. 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