{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T20:42:34Z","timestamp":1762202554057,"version":"build-2065373602"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["esskajournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The durability and effectiveness of total knee arthroplasty (TKA) depend on secure implant fixation and efficient bone integration. While cemented tibial components provide immediate mechanical stability, the addition of a short stem may be indicated in selected cases to enhance fixation. However, the stem does not allow for biological integration. The advantages of cementation over press\u2010fit fixation remain a subject of debate, particularly regarding their impact on periprosthetic bone mineral density (BMD) over time. This study aims to compare periprosthetic BMD changes between cemented and noncemented tibial stems in primary TKA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this prospective, monocentric study, we compared periprosthetic BMD changes in 60 patients undergoing primary TKA, randomised into two groups: 30 with cemented and 30 with noncemented tibial stems. Dual\u2010energy X\u2010ray absorptiometry (DEXA) measured BMD preoperatively and at 3, 6, 12 and 24 months postoperatively across six zones: beneath the tibial tray (R1, R2), around the stem (R3, R4), at the apex (R5), and a control zone below the stem (R6). Statistical analyses included repeated measures analysis of variance and independent\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Cemented stems showed a significant increase in BMD at 12 months (+0.10\u2009g\/cm\u00b2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03) and 24 months (+0.12\u2009g\/cm\u00b2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), outperforming noncemented stems (+0.06\u2009g\/cm\u00b2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.12). Overall, cemented stems demonstrated greater BMD gains (+0.15\u2009g\/cm\u00b2 vs. +0.08\u2009g\/cm\u00b2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03). Minimal changes were observed in both groups, with cemented stems showing slightly higher BMD retention (+0.05\u2009g\/cm\u00b2 vs. \u22120.02\u2009g\/cm\u00b2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.09). No statistically significant differences were recorded in certain regions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Cemented stems demonstrated greater periprosthetic BMD retention, which may contribute to improved mechanical environment for the implant. These findings may help guide the selection of fixation methods in primary TKA, particularly for patients with compromised bone quality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level I.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ksa.12758","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T17:19:22Z","timestamp":1751476762000},"page":"3866-3872","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prospective insights into tibial stems, cemented versus uncemented in primary total knee arthroplasty: A dual\u2010energy X\u2010ray absorptiometry study"],"prefix":"10.1002","volume":"33","author":[{"given":"Rudy","family":"Sangaletti","sequence":"first","affiliation":[{"name":"Unit\u00e0 di Chirurgia Robotica, U.O.C. Ortopedia e Traumatologia Fondazione Poliambulanza Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Polizzi","sequence":"additional","affiliation":[{"name":"U.O.C. Ortopedia e Traumatologia Fondazione Poliambulanza Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Capece","sequence":"additional","affiliation":[{"name":"U.O.C. Ortopedia e Traumatologia Fondazione Poliambulanza Brescia Italy"},{"name":"Universit\u00e0 Cattolica del Sacro Cuore Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Andriollo","sequence":"additional","affiliation":[{"name":"U.O.C. Ortopedia e Traumatologia Fondazione Poliambulanza Brescia Italy"},{"name":"Universit\u00e0 Cattolica del Sacro Cuore Roma Italy"},{"name":"Artificial Intelligence Center Alma Mater Europaea University Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Bna","sequence":"additional","affiliation":[{"name":"U.O. Radiologia Fondazione Poliambulanza Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Benazzo","sequence":"additional","affiliation":[{"name":"U.O.C. Ortopedia e Traumatologia Fondazione Poliambulanza Brescia Italy"},{"name":"IUSS Istituto Universitario di Studi Superiori Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4395-8457","authenticated-orcid":false,"given":"Stefano M. P.","family":"Rossi","sequence":"additional","affiliation":[{"name":"Unit\u00e0 di Chirurgia Robotica, U.O.C. Ortopedia e Traumatologia Fondazione Poliambulanza Brescia Italy"},{"name":"U.O.C. Ortopedia e Traumatologia Fondazione Poliambulanza Brescia Italy"},{"name":"Department of Life Science, Health, and Health Professions Universit\u00e0 degli Studi \u201cLink Campus University\u201d Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.02.032"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-018-4095-4"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2020.04.014"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.95B3.29586"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1678686"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-020-05860-6"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-024-05342-2"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/17453674.2016.1173982"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-012-1601-y"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.5792\/ksrr.18.019"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2019.10.027"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2015.05.049"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-015-2852-1"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2022.03.007"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-021-06800-8"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1385\/JCD:7:4:424"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-018-5130-0"}],"container-title":["Knee Surgery, Sports Traumatology, Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ksa.12758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T20:30:42Z","timestamp":1762201842000},"score":1,"resource":{"primary":{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/10.1002\/ksa.12758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,2]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/ksa.12758"],"URL":"https:\/\/doi.org\/10.1002\/ksa.12758","archive":["Portico"],"relation":{},"ISSN":["0942-2056","1433-7347"],"issn-type":[{"type":"print","value":"0942-2056"},{"type":"electronic","value":"1433-7347"}],"subject":[],"published":{"date-parts":[[2025,7,2]]},"assertion":[{"value":"2025-03-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}