{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T08:17:21Z","timestamp":1789719441955,"version":"4.0.1"},"reference-count":45,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["esskajournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Robotic arm\u2010assisted unicompartmental knee arthroplasty (raUKA) offers potential advantages over robotic arm\u2010assisted total knee arthroplasty (raTKA), but its biological benefits remain unclear. Superior early recovery after raUKA may be related to reduced systemic inflammation and blood loss. It was hypothesised that raUKA would elicit a lower systemic inflammatory response and result in reduced perioperative blood loss compared with raTKA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Patients undergoing raUKA with the Mako\u00ae system were 1:1 propensity score\u2010matched to raTKA patients based on age, gender, body mass index, and ASA score, yielding two balanced cohorts (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009162 each). Blood samples were collected preoperatively, 6\u2009h postoperatively, and on postoperative Days 3 and 5. Primary outcomes were C\u2010reactive protein (CRP) and white blood cell (WBC) levels; secondary outcomes included operative time and calculated blood loss.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      CRP increases were significantly lower after raUKA on Day 3 (1.6 vs. 4.6\u2009mg\/dL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and Day 5 (0.8 vs. 3.7\u2009mg\/dL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.031). WBC counts were lower at 6\u2009h in raUKA (3.8 vs. 4.5\u2009G\/L,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.041) but not significantly different on Days 3 or 5. Median operative time was shorter with raUKA (81 vs. 95\u2009minutes,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Haemoglobin decrease and estimated blood loss were reduced in raUKA compared with raTKA (532 vs. 669\u2009mL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This is the first study to directly compare inflammatory response and blood loss between raUKA and raTKA. raUKA was associated with lower CRP and early WBC elevations, reduced blood loss, and shorter operative times. These results provide clinically relevant biomarker reference values and highlight perioperative advantages of raUKA. Collectively, they support raUKA as a less invasive alternative to raTKA in appropriately selected patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, retrospective comparative study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ksa.70212","type":"journal-article","created":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T16:51:11Z","timestamp":1765126271000},"page":"3339-3347","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Reduced postoperative inflammation and blood loss after robotic arm\u2010assisted unicompartmental compared with total knee arthroplasty: A propensity score\u2010matched 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School of Medicine, Klinikum Rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9678-0656","authenticated-orcid":false,"given":"Vincent","family":"Lallinger","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, School of Medicine, Klinikum Rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4014-424X","authenticated-orcid":false,"given":"Michael T.","family":"Hirschmann","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Traumatology Kantonsspital Baselland (Bruderholz, Liestal, Laufen) Bruderholz Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2352-1357","authenticated-orcid":false,"given":"R\u00fcdiger","family":"von 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