{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T18:17:34Z","timestamp":1789928254042,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["esskajournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To systematically review the literature and perform a single\u2010arm meta\u2010analysis to evaluate clinical outcomes, failure rates and survivorship following fresh osteochondral allograft transplantation of the femoral head.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses guidelines using PubMed, Ovid MEDLINE and Scopus. Clinical studies reporting outcomes of fresh osteochondral allograft transplantation of the femoral head with a minimum follow\u2010up of 12 months were included. A single\u2010arm random\u2010effects meta\u2010analysis of proportions was performed to estimate the pooled rate of conversion to total hip arthroplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eight studies comprising 145 hips were included. The mean patient age ranged from 21 to 26 years, with a mixed sex distribution across studies. Mean follow\u2010up ranged from 17.2 to 79.2 months. Indications were heterogeneous and included osteonecrosis, osteochondritis dissecans, post\u2010traumatic chondral defects and sequelae of Legg\u2013Calv\u00e9\u2013Perthes disease. Patient\u2010reported outcomes improved postoperatively across all studies reporting pre\u2010 and postoperative data. Individual study failure rates ranged from 17.7% to 37.5% at final follow\u2010up. Pooled analysis using a single\u2010arm random\u2010effects meta\u2010analysis demonstrated an overall conversion rate of 26.7% (95% confidence interval, 20.1%\u201334.7%), with low heterogeneity (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090%). Reported survivorship ranged from 68.8% to 93.8% at 2\u20135 years and approximately 62%\u201367% at 9\u201310 years in studies providing long\u2010term data. Overall methodological quality was moderate, with MINORS scores ranging from 10 to 12.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Fresh osteochondral allograft transplantation of the femoral head is associated with postoperative improvement in patient\u2010reported outcomes and achieves joint preservation in the majority of patients at mid\u2010term follow\u2010up. However, approximately one\u2010quarter of treated hips progressed to total hip arthroplasty during follow\u2010up, indicating that failure remains a clinically relevant risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level IV systematic review.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ksa.70397","type":"journal-article","created":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T13:00:48Z","timestamp":1776171648000},"page":"2224-2235","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical improvement but substantial arthroplasty risk following fresh osteochondral allograft transplantation of the femoral head: A systematic review and single\u2010arm meta\u2010analysis"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7045-3222","authenticated-orcid":false,"given":"Napatpong","family":"Thamrongskulsiri","sequence":"first","affiliation":[{"name":"Sports Medicine Research Group, Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Department of Anatomy, Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Department of Orthopaedics, Faculty of Medicine Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5293-5428","authenticated-orcid":false,"given":"Danaithep","family":"Limskul","sequence":"additional","affiliation":[{"name":"Sports Medicine Research Group, Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Department of Orthopaedics, Faculty of Medicine Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanathep","family":"Tanpowpong","sequence":"additional","affiliation":[{"name":"Sports Medicine Research Group, Faculty of Medicine Chulalongkorn University Bangkok Thailand"},{"name":"Department of Orthopaedics, Faculty of Medicine Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7256-4057","authenticated-orcid":false,"given":"Somsak","family":"Kuptniratsaikul","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Faculty of Medicine Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8640-1651","authenticated-orcid":false,"given":"Thun","family":"Itthipanichpong","sequence":"additional","affiliation":[{"name":"Sports Medicine Research Group, Faculty of Medicine Chulalongkorn University Bangkok 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