{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T09:06:22Z","timestamp":1775120782587,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,1,4]],"date-time":"2009-01-04T00:00:00Z","timestamp":1231027200000},"content-version":"vor","delay-in-days":8192,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[1986,8]]},"abstract":"<jats:p>Injectable collagen appears to be safe and effective in treating glottic insufficiency. Fifty\u2010four patients received vocal\u2010fold injections of Zyderm Collagen Implant\u00ae and their responses were followed for as long as 2 years. Videostroboscopy affords the best assessment of glottic function and correlates well with vocal quality. Maximum phonation time and transglottic airflow are the most sensitive measures of glottic efficiency; follow\u2010up studies indicate that responses to treatment vary at 1 week, tend to stabilize by 3 months, and show only slight decrement over 1 year.<\/jats:p><jats:p>One patient experienced a delayed hypersensitivity reaction, but it did not adversely affect his result. The use of cross\u2010linked preparations of collagen should decrease the incidence of such responses.<\/jats:p><jats:p>Treated patients were divided into diagnostic groups. Patients with bilaterally scarred vocal folds did not appear to respond optimally to collagen injection. Vocal rehabilitation was better if patients had at least one normal vocal fold. The best results occurred in patients with unilateral vocal fold paralysis and pre\u2010existent bowing or atrophy did not affect these results. Collagen should be injected in the plane of the vocal ligament for best results; if the injection is too deep the implant is resorbed, and if too superficial, vocal\u2010fold vibration is impaired.<\/jats:p>","DOI":"10.1002\/lary.1986.96.8.863","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T14:26:54Z","timestamp":1488205614000},"page":"863-869","source":"Crossref","is-referenced-by-count":90,"title":["Clinical Experience with Injectable Collagen for Vocal Fold Augmentation"],"prefix":"10.1002","volume":"96","author":[{"given":"Charles N.","family":"Ford","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane M.","family":"Bless","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,1,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016488209130907"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948309200512"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03340480059030"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196509000-00001"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1962.00740050368013"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198404000-00016"},{"key":"e_1_2_1_8_1","first-page":"402","article-title":"Vocal Cord Augmentation: Characteristics of Collagen Versus Teflon in the Canine Larynx","volume":"2","author":"Feder R. J.","year":"1985","journal-title":"Proceedings of the XIII World Congress of Otolaryngology"},{"key":"e_1_2_1_9_1","volume-title":"Submitted as a Candidate's Thesis to The Triological Society","author":"Ford C. N.","year":"1985"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988609400117"},{"key":"e_1_2_1_11_1","unstructured":"Remacle M. Marbaix E. and Bertrand B.: Use of Injectable Collagen for Vocal and Glottic Rehabilitation. Presented at the XII World Congress of Otolaryngology Miami 1985."},{"key":"e_1_2_1_12_1","unstructured":"Sataloff R. S. and Gould W. J.: Personal Correspondence."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)80271-6"},{"key":"e_1_2_1_14_1","unstructured":"Yoshida T. and Hirano M.: A Longitudinal Study of Silicone Injections to Correct Laryngeal Paralysis. Presented at the Eastern Otolaryngology Conference on Phonosurgery Shikoku Island Japan January 11 1986."}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.1986.96.8.863","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.1986.96.8.863","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.1986.96.8.863","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T00:49:18Z","timestamp":1697676558000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.1986.96.8.863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,8]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1986,8]]}},"alternative-id":["10.1002\/lary.1986.96.8.863"],"URL":"https:\/\/doi.org\/10.1002\/lary.1986.96.8.863","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,8]]}}}