{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T07:54:19Z","timestamp":1769500459544,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T00:00:00Z","timestamp":1244160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives\/Hypothesis:<\/jats:title><jats:p>To determine if there is a relationship between <jats:italic>Helicobacter pylori<\/jats:italic> colonization in the pharynx mucous membrane and chronic nonspecific pharyngitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design:<\/jats:title><jats:p>A prospective clinical study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Seventy patients with chronic pharyngitis and 20 healthy control subjects were examined with polymerase chain reaction (PCR) and culture for <jats:italic>H. pylori<\/jats:italic> colonization in the pharynx mucous membrane between March 2008 and October 2008. Patients with pharyngitis were seperated into two groups (35 patients in each) by using C\u201014 urea breath test, according to the presence of gastric <jats:italic>H. pylori<\/jats:italic> infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>In the control group, none of the patients had <jats:italic>H. pylori<\/jats:italic> in the pharynx. In the chronic pharyngitis group, in 12 patients (34.3%) with gastric <jats:italic>H. pylori<\/jats:italic> infection and in seven patients (20%) without gastric infection, <jats:italic>H. pylori<\/jats:italic> colonization in pharynx mucosa was determined with the PCR method. In only two of chronic pharyngitis patients (5.8%), <jats:italic>H. pylori<\/jats:italic> infection was detected with culture. In the pharynx mucosa, the <jats:italic>H. pylori<\/jats:italic> infection rate was significantly higher in the chronic pharyngitis groups than in the control group (<jats:italic>P<\/jats:italic> = .002 between C\u201014 positive and control groups, <jats:italic>P<\/jats:italic> = .040 between C\u201014 negative and control groups). There was not a significant difference in <jats:italic>H. pylori<\/jats:italic> colonization in the pharynx of patients who had chronic pharyngitis with or without gastric ailments and <jats:italic>H. pylori<\/jats:italic> infection (<jats:italic>P<\/jats:italic> = .179).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Chronic nonspecific pharyngitis without gastric <jats:italic>H. pylori<\/jats:italic> infection is significantly related to <jats:italic>H. pylori<\/jats:italic> colonization in the pharynx, and gastric involvement increases the rate of this spread. The gold standart for detection of <jats:italic>H. pylori<\/jats:italic> infection is the PCR method. Laryngoscope, 2009<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.20253","type":"journal-article","created":{"date-parts":[[2009,6,6]],"date-time":"2009-06-06T11:03:45Z","timestamp":1244286225000},"page":"1479-1483","source":"Crossref","is-referenced-by-count":15,"title":["Determination of <i>Helicobacter pylori<\/i> in patients with chronic nonspecific pharyngitis"],"prefix":"10.1002","volume":"119","author":[{"given":"Zeynep 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