{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T04:15:58Z","timestamp":1773375358422,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T00:00:00Z","timestamp":1244160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives\/Hypothesis:<\/jats:title><jats:p>Laryngopharyngeal reflux (LPR) represents a challenging field. Therapeutic studies of proton pump inhibitors in LPR have shown mixed results. The Restech pH catheter (Respiratory Technology Corp., San Diego, CA) is a minimally invasive device for detection of oropharyngeal acid reflux. The aim of this study was to provide normative data using this device in both distal esophagus and oropharynx.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design:<\/jats:title><jats:p>Prospective observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Normal volunteers were recruited to undergo pH monitoring. A custom made longer catheter was used to assess distal esophageal pH. Oropharyngeal pH catheter was placed at the level of uvula. The distribution of % time was summarized using the 5th, 25th, 50th (median), 75th, and 95th quantiles for pH &lt; 6, pH &lt; 5, and pH &lt; 4 for both upright and supine positions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>A total of 20 normal, healthy volunteers underwent pH monitoring for 14 to 24 hours (median 20.5 hours). The 95th percentile for % total time pH &lt; 4, pH &lt; 5, pH &lt; 6 for the distal esophageal pH catheter were 4.52%, 10.91%, and 42.99%, respectively. For the oropharynx pH probe, the 95th percentile for % total time pH &lt; 4, pH &lt; 5, and pH &lt; 6 were 0.02%, 2.33%, and 21.41% respectively. The 95th percentile for number of reflux events for total pH &lt; 4, pH &lt; 5, and pH &lt; 6 were 1.3, 8.1, and 128.0, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Oropharyngeal acid reflux is an infrequent occurrence in healthy volunteers without LPR. The normative data for Restech pH catheter may now be compared to those with suspected LPR. Laryngoscope, 2009<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.20282","type":"journal-article","created":{"date-parts":[[2009,6,6]],"date-time":"2009-06-06T10:59:54Z","timestamp":1244285994000},"page":"1639-1643","source":"Crossref","is-referenced-by-count":91,"title":["A new pH catheter for laryngopharyngeal reflux: Normal values"],"prefix":"10.1002","volume":"119","author":[{"given":"George","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srikant","family":"Muddana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James C.","family":"Slaughter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean","family":"Casey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farnoosh","family":"Farrokhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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