{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T08:20:19Z","timestamp":1759134019012},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2009,8,17]],"date-time":"2009-08-17T00:00:00Z","timestamp":1250467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives\/Hypothesis:<\/jats:title><jats:p>To assess the risk of level V nodal involvement for early T\u2010stage and node positive oropharyngeal squamous cell carcinoma (ORO\u2010SCC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Retrospective analysis performed on patients with ORO\u2010SCC and clinically positive lymph nodes who had undergone upfront elective dissection of level V before definitive chemoradiotherapy. Pathological data collected and prevalence of involvement of level V determined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>A total of 119 patients had level V dissection. The prevalence of pathologically positive lymph nodes in level V was 3.4% (4\/119). Moreover, it was observed only in the presence of pathological involvement of multiple other nodal levels (4\/52 patients, 7.7% vs. 0\/67 in patients with a single nodal station involved, \u03c7<jats:sup>2<\/jats:sup><jats:italic>P<\/jats:italic> = .02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Subclinical involvement of level V in ORO\u2010SCC is rare, especially in the presence of disease confined to a single nodal level. The present data do not support its dissection after primary chemoradiotherapy. Laryngoscope, 2009<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.20616","type":"journal-article","created":{"date-parts":[[2009,8,17]],"date-time":"2009-08-17T21:26:26Z","timestamp":1250544386000},"page":"2165-2169","source":"Crossref","is-referenced-by-count":9,"title":["Level V involvement in patients with early T\u2010stage, node\u2010positive oropharyngeal carcinoma"],"prefix":"10.1002","volume":"119","author":[{"given":"Kavita M.","family":"Pattani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Califano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Sanguineti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,8,17]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semradonc.2008.09.005"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000154729.31281.da"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1977.01370030036005"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(83)90246-5"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.5.486"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000217543.40027.1d"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2008.05.004"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2005.12.023"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(05)70077-3"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.177.2.2217772"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20842"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.1144"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(05)80554-9"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.8.950"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199803)20:2<132::AID-HED6>3.0.CO;2-3"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000162648.37638.76"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10315"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318165e33e"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(05)80340-X"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000182475.49177.72"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000224363.04459.8b"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20976"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200004000-00016"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1006\/ijom.2003.0507"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.130.2.149"},{"key":"e_1_2_6_27_2","first-page":"23","volume-title":"Head and Neck Cancer: An Evidence\u2010Based Team Approach","author":"Genden EM","year":"2008"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.20616","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.20616","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:28:33Z","timestamp":1697502513000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.20616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,17]]},"references-count":26,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["10.1002\/lary.20616"],"URL":"https:\/\/doi.org\/10.1002\/lary.20616","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,17]]}}}