{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:02:19Z","timestamp":1792731739173,"version":"4.5.0"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,3,19]],"date-time":"2010-03-19T00:00:00Z","timestamp":1268956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives\/Hypothesis:<\/jats:title>\n                    <jats:p>To evaluate the impact of steroid\u2010impregnated absorbable nasal dressing on wound healing and surgical outcomes after endoscopic sinus surgery (ESS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>A prospective, randomized, double\u2010blinded, placebo\u2010controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Chronic rhinosinusitis patients with polyposis who were to undergo bilateral endoscopic sinus surgery were recruited and randomized to receive triamcinolone\u2010impregnated bioresorbable dressing (Nasopore; Stryker Canada, Hamilton, Ontario, Canada) in one nasal cavity and saline\u2010impregnated dressing contralaterally. Postoperative healing assessments of edema, crusting, secretions, and scarring were done at postoperative days 7, 14, 28 and at 3 and 6 months using validated Lund\u2010Kennedy and Perioperative Sinus Endoscopy (POSE) scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Analysis of 19 enrolled patients having completed observation shows no significant difference between the cavity scores preoperatively using both the POSE and Lund\u2010Kennedy scores. There was, however, a statistically significant difference at day 7 and 14 in both the Lund\u2010Kennedy (\n                      <jats:italic>P<\/jats:italic>\n                      = .04 and\n                      <jats:italic>P<\/jats:italic>\n                      = .03, respectively) and POSE scores (\n                      <jats:italic>P<\/jats:italic>\n                      = .03 and P = .001, respectively) for the treatment and control groups, and a significant difference was also detected between the groups at 3\u2010 and 6\u2010month observations (Lund\u2010Kennedy,\n                      <jats:italic>P<\/jats:italic>\n                      = .007 and\n                      <jats:italic>P<\/jats:italic>\n                      = .02, respectively; POSE,\n                      <jats:italic>P<\/jats:italic>\n                      = .049 and\n                      <jats:italic>P<\/jats:italic>\n                      = .01, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Data analysis suggests a significant improvement in early postoperative healing in nasal cavities receiving triamcinolone\u2010impregnated absorbable nasal packing following ESS and is also associated with improved healing up to 6 months postoperatively.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.20905","type":"journal-article","created":{"date-parts":[[2010,3,20]],"date-time":"2010-03-20T19:27:16Z","timestamp":1269113236000},"page":"1269-1273","source":"Crossref","is-referenced-by-count":113,"title":["Triamcinolone\u2010impregnated nasal dressing following endoscopic sinus surgery: A randomized, double\u2010blind, placebo\u2010controlled study"],"prefix":"10.1002","volume":"120","author":[{"given":"David W. J.","family":"C\u00f4t\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin D.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,5,21]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199301000-00001"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/194589240602000102"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2007.21.3011"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.10.028"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200023040-00004"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2004.02044.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/014556139607500811"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31814842f8"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989770005-6"},{"key":"e_1_2_6_11_2","first-page":"183","article-title":"Staging in rhinosinusitis","volume":"107","author":"Lund VJ","year":"1993","journal-title":"Rhinology"},{"key":"e_1_2_6_12_2","first-page":"107","article-title":"Intra\u2010 and postoperative application of Mitomycin C in the middle meatus reduces adhesions and antrostomy stenosis after FESS","volume":"46","author":"Konstantinidis I","year":"2008","journal-title":"Rhinology"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/194589240401800509"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2008.22.3171"},{"key":"e_1_2_6_15_2","first-page":"68","article-title":"The effect of nasal packing and prednisolone on mucosal healing and reciliation in a sheep model","volume":"42","author":"Robinson S","year":"2004","journal-title":"Rhinology"},{"key":"e_1_2_6_16_2","first-page":"112","article-title":"Prospective, double\u2010blind, randomized trial evaluating patient satisfaction, bleeding, and wound healing using biodegradable synthetic polyurethane foam (NasoPore) as a middle meatal spacer in functional endoscopic sinus surgery","volume":"38","author":"Shoman N","year":"2009","journal-title":"J Otolaryngol Head Neck Surg"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.20905","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.20905","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.20905","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T23:58:35Z","timestamp":1696895915000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.20905"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,21]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1002\/lary.20905"],"URL":"https:\/\/doi.org\/10.1002\/lary.20905","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.4242991.4039100","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.4242991.4743055","asserted-by":"object"}]},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,21]]}}}