{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:18:28Z","timestamp":1791976708463,"version":"4.4.0"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2010,9,7]],"date-time":"2010-09-07T00:00:00Z","timestamp":1283817600000},"content-version":"vor","delay-in-days":62,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives:<\/jats:title><jats:p>Laryngeal electromyography (LEMG) is primarily a qualitative examination, with no standardized approach to interpretation. The objectives of our study were to establish quantitative norms for motor unit recruitment in controls and to compare with interference pattern analysis in patients with unilateral vocal fold paralysis (VFP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design:<\/jats:title><jats:p>Retrospective case\u2013control study<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>We performed LEMG of the thyroarytenoid\u2010lateral cricoarytenoid muscle complex (TA\u2010LCA) in 21 controls and 16 patients with unilateral VFP. Our standardized protocol used a concentric needle electrode with subjects performing variable force TA\u2010LCA contraction. To quantify the interference pattern density, we measured turns and mean amplitude per turn for \u226510 epochs (each 500 milliseconds). Logarithmic regression analysis between amplitude and turns was used to calculate slope and intercept. Standard deviation was calculated to further define the confidence interval, enabling generation of a linear\u2010scale graphical \u201ccloud\u201d of activity containing \u226590% of data points for controls and patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Median age of controls and patients was similar (50.7 vs. 48.5 years). In controls, TA\u2010LCA amplitude with variable contraction ranged from 145\u20131112 \u03bcV, and regression analysis comparing mean amplitude per turn to root\u2010mean\u2010square amplitude demonstrated high correlation (<jats:italic>R<\/jats:italic> = 0.82). In controls performing variable contraction, median turns per second was significantly higher compared to patients (450 vs. 290, <jats:italic>P<\/jats:italic> = .002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>We first present interference pattern analysis in the TA\u2010LCA in healthy adults and patients with unilateral VFP. Our findings indicate that motor unit recruitment can be quantitatively measured within the TA\u2010LCA. Additionally, patients with unilateral VFP had significantly reduced turns when compared with controls. Laryngoscope, 2010<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.21046","type":"journal-article","created":{"date-parts":[[2010,7,7]],"date-time":"2010-07-07T19:59:47Z","timestamp":1278532787000},"page":"2036-2041","source":"Crossref","is-referenced-by-count":63,"title":["Quantitative laryngeal electromyography: Turns and amplitude analysis"],"prefix":"10.1002","volume":"120","author":[{"given":"Melissa McCarty","family":"Statham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clark A.","family":"Rosen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev D.","family":"Nandedkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Munin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,7,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(03)00146-1"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.01.026"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(83)90035-4"},{"key":"e_1_2_6_5_2","first-page":"560","article-title":"Functional significance of cell size in spinal motor neurons","volume":"28","author":"Henneman E","year":"1965","journal-title":"Ann Plast Surg"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-199609000-00004"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(05)70242-5"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016489009125171"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.2217\/14796708.3.6.745"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880151204"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880140103"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880090507"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880090604"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(88)90151-4"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016489109100770"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880151205"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.21046","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.21046","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T04:24:11Z","timestamp":1697516651000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.21046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,7]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["10.1002\/lary.21046"],"URL":"https:\/\/doi.org\/10.1002\/lary.21046","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,7]]}}}