{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T05:04:32Z","timestamp":1748927072819},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,11,4]],"date-time":"2010-11-04T00:00:00Z","timestamp":1288828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>Many children with cervicofacial lymphatic malformations have facial skeletal abnormalities. This study qualitatively and quantitatively evaluated these bony mandibular abnormalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with craniofacial lymphatic malformations presenting to a vascular anomalies center during a 2\u2010year period were included. An age\u2010matched control population was found on the Picture Archiving and Communication System database. Three\u2010dimensional reconstructions were created from computed tomography and magnetic resonance imaging. Qualitative observations and quantitative measurements were taken of the gonial angle, mandibular anterior dentoalveolar height, and anterior condylar displacement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 23 controls. A total of 21 patients with \u201cbeard\u201d distribution malformations were studied; 10 had unilateral and 11 had bilateral disease.<\/jats:p><jats:p>Qualitatively, a few patterns emerged: outward ramal flaring, anterior displacement of the mandible, relative ipsilateral facial \u201chypertrophy,\u201d and anterior positioning of the maxilla and orbit. The open\u2010bite deformity was a common finding leading to malocclusion and oral incompetence. Quantitatively, in 67 nondiseased sides, the average gonial angle was 131 degrees (standard deviation [SD] = 6.8), whereas in 32 diseased sides, the average angle was 152 degrees (SD = 14.0, <jats:italic>P<\/jats:italic> &lt; 3.8E\u201009). With half\u2010beard malformations, the diseased side averaged 153.9 and the nondiseased side averaged 140.8 (<jats:italic>P<\/jats:italic> = .008). The average condylar displacement was 8.5 mm versus 5.9 mm (diseased vs. nondiseased), and the average mandibular dentoalveolar height to face ratio was 0.37 (control = 0.34).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cervicofacial lymphatic malformations in the \u201cbeard\u201d distribution are associated with significant bony abnormalities leading to both functional and aesthetic sequelae. Our study is the first quantitative analysis of these changes. This is the first step in planning for dentofacial orthopedics, orthodontics, and orthognathic surgery. Laryngoscope, 2011<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.21161","type":"journal-article","created":{"date-parts":[[2010,8,31]],"date-time":"2010-08-31T15:58:11Z","timestamp":1283270291000},"page":"91-101","source":"Crossref","is-referenced-by-count":10,"title":["Analysis of skeletal mandibular abnormalities associated with cervicofacial lymphatic malformations"],"prefix":"10.1002","volume":"121","author":[{"given":"Teresa M.","family":"O","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roy","family":"Kwak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"E. Portnof","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daryl M.","family":"Berke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Lipari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milton","family":"Waner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,11,4]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1413.016"},{"key":"e_1_2_7_3_2","volume-title":"Hemangiomas and Vascular Malformations of the Head and Neck.","author":"Waner M","year":"1999"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0007-117X(78)90022-7"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198412000-00010"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199505000-00001"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(87)90156-X"},{"issue":"5","key":"e_1_2_7_8_2","first-page":"129","article-title":"A proposal for a new analysis of craniofacial morphology by 3\u2010dimensional computed tomography","author":"Park SH","year":"2006","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hym050"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100147176"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-196604000-00001"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-199001020-00005"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000239104.78390.E5"},{"key":"e_1_2_7_14_2","first-page":"1137","article-title":"Treatment of lymphangiomas in children: an update of Picibanil (OK\u2010432) sclerotherapy","volume":"128","author":"Giguere CM","year":"1999","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-4356(96)90002-9"},{"key":"e_1_2_7_16_2","first-page":"191","article-title":"Orthognathic surgery: a hierarchy of stability","volume":"11","author":"Proffit WR","year":"1996","journal-title":"Int J Adult Orthodon Orthognath Surg"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/1746-160X-3-21"},{"key":"e_1_2_7_18_2","first-page":"848","volume-title":"Craniomaxillofacial surgery in the pediatric patient: growth and development considerations.","author":"Costello BJ","year":"2009"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(96)90039-1"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1997.01900100035004"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.21161","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.21161","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T12:00:01Z","timestamp":1700481601000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.21161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,4]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1002\/lary.21161"],"URL":"https:\/\/doi.org\/10.1002\/lary.21161","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,4]]}}}