{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T04:14:45Z","timestamp":1784693685390,"version":"3.55.0"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,3,23]],"date-time":"2011-03-23T00:00:00Z","timestamp":1300838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim:<\/jats:title><jats:p>To examine if a Gelfoam\u00ae plug in combination with surgical removal of the perforation edges could be an alternative to the widely accepted fat plug treatment for smaller ear drum perforations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>A prospective study of 17 consecutive patients with persistent small ear drum perforations considered for myringoplasty. The perforations were central perforations 2 to 4 mm in diameter. Patient ages ranged from 6 to 83 years, and the operation was performed under general anesthesia with mask ventilation in children and under topical local anesthesia in adults. A Gelfoam\u00ae plug was inserted into the perforation after surgical removal of the perforation edges. The follow\u2010up time was more than 3 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>The closure rate of the ear drum was 83% (15\/18). Pure tone average (PTA) was 19 dB preoperatively and 16 dB postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>We show for the first time in humans that a Gelfoam\u00ae plug in combination with surgical removal of the perforation edges seems to result in about the same closure rate as the fat plug technique in persistent small ear drum perforations. Moreover, the method using Gelfoam\u00ae is simpler and faster than the fat plug technique. We suggest that randomized studies comparing the Gelfoam\u00ae plug technique with the fat plug technique should be performed. Laryngoscope, 2011<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.21451","type":"journal-article","created":{"date-parts":[[2011,3,23]],"date-time":"2011-03-23T18:51:36Z","timestamp":1300906296000},"page":"782-784","source":"Crossref","is-referenced-by-count":46,"title":["The Gelfoam\u00ae plug: An alternative treatment for small eardrum perforations"],"prefix":"10.1002","volume":"121","author":[{"given":"Anders","family":"Niklasson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krister","family":"Tano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,3,23]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.5540680706"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.01.003"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59980300124-4"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000276182"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196202000-00005"},{"key":"e_1_2_6_7_2","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1017\/S002221510013659X","article-title":"Fat graft myringoplasty in children\u2014a safe and successful day\u2010stay procedure","volume":"111","author":"Michell RB","year":"1997","journal-title":"J Laryngol Otol"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.2310\/7070.2005.4124"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2004.08.001"},{"key":"e_1_2_6_10_2","first-page":"362","article-title":"Gelfoam\/gelfilm patching following the remowal of ventilation tubes","volume":"24","author":"Hekkenberg RJ","year":"1995","journal-title":"J Otolaryngol"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016488309132899"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196211000-00003"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.21451","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.21451","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T11:59:18Z","timestamp":1700481558000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.21451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,23]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1002\/lary.21451"],"URL":"https:\/\/doi.org\/10.1002\/lary.21451","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,23]]}}}