{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:01:58Z","timestamp":1791403318034,"version":"4.3.3"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,6,6]],"date-time":"2011-06-06T00:00:00Z","timestamp":1307318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective:<\/jats:title><jats:p>To review the clinical presentation, surgical techniques, and outcomes of the transmastoid extradural\u2013intracranial (TMEDIC) approach for the treatment of transtemporal meningoencephalocele.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis:<\/jats:title><jats:p>The TMEDIC is a safe and effective approach to repair meningoencephalocele originating from the middle or posterior cranial fossa.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design:<\/jats:title><jats:p>Retrospective chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting:<\/jats:title><jats:p>Academic neurotologic tertiary referral center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients:<\/jats:title><jats:p>Thirty\u2010one consecutive patients diagnosed with transpetrous meningo(encephalo)cele, with or without cerebrospinal fluid leak, between January of 2003 and October of 2010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Intervention:<\/jats:title><jats:p>TMEDIC approach for repairing herniated neural tissue through the tegmen or posterior fossa plate using the combination of autologous cartilage, fascia, and tissue sealant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures:<\/jats:title><jats:p>Anatomic location, size, and number of defects, presence of herniated brain tissue, pre\u2010 and postoperative hearing thresholds, and failure rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Mean age was 62 \u00b1 26 years. The etiology was spontaneous in 25\/31 (80%), congenital in 3\/31 (10%), chronic otitis media in 2\/31 (6%), and posttraumatic in 1\/31 (4%). Posttympanostomy tube clear otorrhea was the presenting sign in 21\/31 (68%) of patients. The mean duration of symptoms was 26 months (range: 1\u2013240). The defect involved the middle fossa (MF) floor in 25\/31 (90%). Both the tegmen tympani and mastoideum were involved in 12\/31 (39%) of patients and multiple dehiscences were seen in 7\/31 (22%). In 17\/31 (55%) of cases the size exceeded 1 cm. No recurrences were seen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>The TMEDIC is a safe and effective method to repair transtemporal meningoencephalocele obviating the need for a middle fossa craniotomy in certain cases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.21887","type":"journal-article","created":{"date-parts":[[2011,6,6]],"date-time":"2011-06-06T16:28:56Z","timestamp":1307377736000},"page":"1765-1772","source":"Crossref","is-referenced-by-count":58,"title":["Transmastoid extradural\u2013intracranial approach for repair of transtemporal meningoencephalocele: A review of 31 consecutive cases"],"prefix":"10.1002","volume":"121","author":[{"given":"Maroun T.","family":"Semaan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Gilpin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel 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