{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T17:00:15Z","timestamp":1781110815360,"version":"3.54.1"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,9,14]],"date-time":"2011-09-14T00:00:00Z","timestamp":1315958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives\/Hypothesis:<\/jats:title><jats:p>To analyze the pattern of the upper airway obstruction in a large cohort of obstructive sleep apnea (OSA) patients using sleep videofluoroscopy (SVF).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design:<\/jats:title><jats:p>Retrospective analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>This study included 922 OSA patients who underwent both polysomnography and SVF. Their mean age, apnea\u2010hypopnea index, and body mass index were 46.8 years, 34.2 per hour, and 26.2 kg\/m<jats:sup>2<\/jats:sup>, respectively. Sleep was induced by intravenous injection of midazolam, and the obstruction pattern was determined on SVF when oxygen saturation dropped by more than 4% in pulse oxymetry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>The anatomic structure and airway level, which were most commonly involved in obstruction, were the soft palate (77.9%) and the oropharynx (88.1%), respectively. The soft palate alone was the most common obstructed structure in mild OSA (43.2%), and the combination of the soft palate and the tongue base was more frequent in severe OSA (45.2%). The tongue base or the hypopharynx was progressively more involved in moderate\/severe OSA cases (<jats:italic>P<\/jats:italic> &lt; .001, respectively), and a multiplicity of obstruction pattern also increased according to OSA severity (<jats:italic>P<\/jats:italic> &lt; .001). However, 32.4% of the patients with mild OSA also had multiple obstructive anatomic structures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Even if multiplicity of obstruction pattern was most commonly associated with severe OSA, almost one third of mild OSA patients also showed multiple anatomic structures and levels of obstruction. Therefore, a precise evaluation for multiplicity of obstruction patterns should precede the decision of a treatment plan, regardless of disease severity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.22344","type":"journal-article","created":{"date-parts":[[2011,9,15]],"date-time":"2011-09-15T03:57:07Z","timestamp":1316059027000},"page":"237-241","source":"Crossref","is-referenced-by-count":39,"title":["Analysis of upper airway obstruction by sleep videofluoroscopy in obstructive sleep apnea"],"prefix":"10.1002","volume":"122","author":[{"given":"Chul 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