{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T12:32:44Z","timestamp":1785241964967,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,1,17]],"date-time":"2012-01-17T00:00:00Z","timestamp":1326758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives\/Hypothesis:<\/jats:title><jats:p>To describe the population of patients with malignancy affecting the ear canal and temporal bone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design:<\/jats:title><jats:p>Retrospective review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>The charts of 157 patients with temporal bone cancer were reviewed for clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Between 1999 and 2009, 157 patients underwent temporal bone surgery for cancer involving the ear canal (n = 25), external ear with ear canal involvement (n = 26), periauricular skin (n = 40), parotid gland (n = 40), temporal bone (n = 13), and lateral skull base (n = 13). All surgeries involved one or more otologic approaches: mastoidectomy (28.0%), lateral temporal bone resection (TBR) (59.2%), subtotal TBR (2.5%), total TBR (3.2%), transtemporal approach (TTA) to the jugular foramen (8.2%), TTA to the middle fossa (5.7%), and TTA to the infratemporal fossa (3.2%). Cancers of the cartilaginous ear canal were managed with wide local excision of canal skin and cartilage in nine patients (5.7%). A combination of approaches was performed in 32 patients (20.4%). The 5\u2010year overall survival rate was 58.0%. Patients whose disease was limited to the ear canal had significantly better overall survival than did patients who had skull base primaries (<jats:italic>P<\/jats:italic> = .02989), periauricular skin cancer (<jats:italic>P<\/jats:italic> = .00138), or temporal bone tumors (<jats:italic>P<\/jats:italic> = .02598). Patients with parotid tumors also had better overall survival than did those with periauricular skin tumors (<jats:italic>P<\/jats:italic> = .02357).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Otologic surgery plays an important role in managing cancers that involve the ear canal, temporal bone, or lateral skull base. The specialty of otologic oncology is emerging as a defined area of practice.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.22402","type":"journal-article","created":{"date-parts":[[2012,1,17]],"date-time":"2012-01-17T19:33:16Z","timestamp":1326828796000},"page":"393-400","source":"Crossref","is-referenced-by-count":58,"title":["The oncology of otology"],"prefix":"10.1002","volume":"122","author":[{"given":"Paul W.","family":"Gidley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher R.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianna B.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"DeMonte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehab Y.","family":"Hanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,17]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"1575","article-title":"Cancer of the middle ear and temporal bone","volume":"74","author":"Conley JJ","year":"1974","journal-title":"N Y State J Med"},{"key":"e_1_2_6_3_2","first-page":"1","article-title":"Temporal bone and lateral skull base malignancy: experience and results with 81 patients","volume":"19","author":"Manolidis S","year":"1998","journal-title":"Am J Otol"},{"key":"e_1_2_6_4_2","first-page":"351","article-title":"Carcinoma of the middle ear and temporal bone","volume":"9","author":"Arena S","year":"1988","journal-title":"Am J Otol"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199610000-00012"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2002.12.5.9"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1975.00780300027006"},{"key":"e_1_2_6_8_2","first-page":"582","article-title":"Squamous cell carcinoma of the external auditory canal: an evaluation of a staging system","volume":"21","author":"Moody SA","year":"2000","journal-title":"Am J Otol"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/019459988509300202"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2002.12.5.3"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2002.02313.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000154744.71184.c7"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21048"},{"key":"e_1_2_6_14_2","first-page":"438","article-title":"Invasion patterns of advanced temporal bone malignancies","volume":"17","author":"Leonetti JP","year":"1996","journal-title":"Am J Otol"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/019459988709600102"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/019459989411000303"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20937"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1992.tb01055.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000190463.88873.3d"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2005.11.012"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.22402","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.22402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T05:50:22Z","timestamp":1700545822000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.22402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,17]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["10.1002\/lary.22402"],"URL":"https:\/\/doi.org\/10.1002\/lary.22402","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,17]]}}}