{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T07:41:30Z","timestamp":1789630890560,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,1,31]],"date-time":"2012-01-31T00:00:00Z","timestamp":1327968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives\/Hypothesis:<\/jats:title><jats:p>The aim of this study was to prospectively evaluate volume change in anterolateral thigh free flaps pre\u2010 and postradiotherapy and to compare computed tomography (CT) volumetric analysis with intraoperative water displacement calculation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design:<\/jats:title><jats:p>Matched pair cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Thirteen patients with advanced carcinoma of the parotid gland underwent anterolateral thigh free flap reconstruction following total parotidectomy resections and neck dissection. Before the initiation of external beam radiation, routine CT planning scans were done on all patients. A minimum of 6 months after surgery, a CT scan of the head and neck was carried out, and a detailed volumetric assessment was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>The mean preradiotherapy flap volume was 94.3 mL, and the postradiotherapy volume was 84.8 mL. The mean volume reduction in all 13 patients was 8.12%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>In this prospective study we observed an 8% volume loss in anterolateral thigh free flaps 6 months postradiotherapy. This loss of volume should be taken into account when reconstructing large defects of the face and lateral skull base. Intraoperative water displacement measurement is a useful adjunctive tool for shaping free tissue transfers that are to be used for volume replacement and soft\u2010tissue fill\u2010in. Laryngoscope, 2012<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.22509","type":"journal-article","created":{"date-parts":[[2012,1,6]],"date-time":"2012-01-06T18:45:04Z","timestamp":1325875504000},"page":"767-772","source":"Crossref","is-referenced-by-count":44,"title":["Volumetric changes of the anterolateral thigh free flap following adjuvant radiotherapy in total parotidectomy reconstruction"],"prefix":"10.1002","volume":"122","author":[{"given":"Kevin M.","family":"Higgins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boban M.","family":"Erovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananth","family":"Ravi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Yeung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin W.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny J.","family":"Enepekides","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2007.05.010"},{"key":"e_1_2_6_3_2","article-title":"Reconstruction of post\u2010radical parotidectomy defects","author":"Ch'ng S","year":"2011","journal-title":"Plast Reconstr Surg"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000135326.50939.C1"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.2310\/7070.2001.19876"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/014556130508400316"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31816dd2e9"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199493030-00004"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2005.02.006"},{"key":"e_1_2_6_10_2","first-page":"566","article-title":"Clinical utility of colour flow Doppler ultrasonography in planning anterolateral thigh flap harvest","volume":"39","author":"Patel RS","year":"2010","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(03)00718-6"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2010.08.014"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20744"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2010.11.001"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3181c46692"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6693"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200107000-00013"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2005.02.005"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.20811"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.22509","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.22509","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T07:21:26Z","timestamp":1700551286000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.22509"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,31]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1002\/lary.22509"],"URL":"https:\/\/doi.org\/10.1002\/lary.22509","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,31]]}}}