{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:45:30Z","timestamp":1760888730432},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T00:00:00Z","timestamp":1338854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives\/Hypothesis:<\/jats:title><jats:p>To evaluate the efficacy of treating lower gum cancer using fluorine\u201018 fluorodeoxyglucose positron\u2010emission tomography\/computed tomography ([18] F\u2010FDG PET\/CT) surgical navigation to control bony margins during segmental mandibulectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design:<\/jats:title><jats:p>This study was conducted between September 2010 and June 2011 in a tertiary referral center in southern Taiwan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Segmental mandibulectomy was performed using surgical navigation via [18] F\u2010FDG PET\/CT. Bony margins after decalcification, the 1\u2010year survival rate, and local control rate were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Ten cases of advanced lower gum cancer in male patients were treated by mandibulectomy, and the bony margins required to excise all neoplastic cells were negative in all cases by using surgical navigation. The minimal distance from the tumor border to the bony incision was 2 cm (2.0\u20132.9 cm). The mean follow\u2010up period was 15.2 months (range, 6\u201324 months) with a 1\u2010year survival rate of 90% and local control rate of 100%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>The segmental mandibulectomy aided by surgical navigation with [18] F\u2010FDG PET\/CT guidance is simple and feasible to ensure adequate bony margins intraoperatively, but more patients are necessary to support these findings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.23461","type":"journal-article","created":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T18:40:06Z","timestamp":1338921606000},"page":"2205-2209","source":"Crossref","is-referenced-by-count":5,"title":["A pilot study of segmental mandibulectomy with surgical navigation using fluorine\u201018 fluorodeoxyglucose positron\u2010emission tomography\/computed tomography"],"prefix":"10.1002","volume":"122","author":[{"given":"Chih\u2010Yen","family":"Chien","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui\u2010Ching","family":"Chuang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu\u2010Hua","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei\u2010Che","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Husan\u2010Ying","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,6,5]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199407000-00023"},{"key":"e_1_2_6_3_2","first-page":"775","article-title":"Staging of untreated squamous cell carcinoma of buccal mucosa with 18F\u2010FDG PET: comparison with head and neck CT\/MRI and histopathology","volume":"46","author":"Yen TC","year":"2005","journal-title":"J Nucl Med"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-009-0586-8"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.09.045"},{"key":"e_1_2_6_6_2","first-page":"101","article-title":"Advanced new neurosurgical procedure using integrated system of intraoperative MRI and neuronavigation with multimodal neuroradiological images","volume":"71","author":"Wakabayashi T","year":"2009","journal-title":"Nagoya J Med Sci"},{"key":"e_1_2_6_7_2","first-page":"106","article-title":"Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA","volume":"31","author":"Giesel FL","year":"2009","journal-title":"Exp Oncol"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0b013e318217566f"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.5.600"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200201000-00008"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000164688.44223.75"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199505000-00004"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21350"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2007.05.004"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2010.02.004"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-010-0870-3"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.23461","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.23461","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T11:47:41Z","timestamp":1700567261000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.23461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,5]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1002\/lary.23461"],"URL":"https:\/\/doi.org\/10.1002\/lary.23461","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,5]]}}}