{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:28:36Z","timestamp":1785551316289,"version":"3.56.0"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,12,3]],"date-time":"2012-12-03T00:00:00Z","timestamp":1354492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To study longitudinal prevalence of otitis media with effusion (OME) in children between 7 and 16 years of age by cleft group, and hearing sensitivity across time and across frequencies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective and longitudinal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All children with cleft palate born from 1991 to 1993 were included in the study (<jats:italic>n<\/jats:italic> = 58). Audiological and otological data were reviewed at 7, 10, 13, and 16 years of age. The group was divided by cleft type (24 unilateral cleft lip and palate, 23 cleft palate only, and 11 bilateral cleft lip and palate).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of abnormal middle ear status decreased significantly with age. When comparing cleft types, the isolated cleft palate group presented with a significantly lower prevalence of abnormal middle ear status than the other groups at 7 and 16 years of age (21% as compared to 32% in the unilateral group and 38% in the bilateral group). The pure\u2010tone average improved with age, while the high\u2010frequency pure\u2010tone average did not. When cleft types were compared, the bilateral group demonstrated significantly poorer hearing in the high frequencies than the other groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children with cleft palate need regular audiological and otological follow\u2010up to ensure management is appropriate and timely. The increased hearing thresholds in the high frequencies may be due to the increased episodes of OME.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2B.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.23839","type":"journal-article","created":{"date-parts":[[2012,12,4]],"date-time":"2012-12-04T05:51:15Z","timestamp":1354600275000},"page":"1374-1380","source":"Crossref","is-referenced-by-count":57,"title":["A longitudinal study of hearing and middle ear status in adolescents with cleft lip and palate"],"prefix":"10.1002","volume":"123","author":[{"given":"Traci","family":"Flynn","sequence":"first","affiliation":[{"name":"Department of Audiology Sahlgrenska University Hospital Department of Audiology University of Gothenburg Gothenburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette","family":"Lohmander","sequence":"additional","affiliation":[{"name":"Department of Clinical Science Intervention and Technique Karolinska Institute and Karolinska University Hospital Stockholm"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claes","family":"Moller","sequence":"additional","affiliation":[{"name":"The Swedish Institute for Disability Research \u00d6rebro University and \u00d6rebro University Hospital \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lennart","family":"Magnusson","sequence":"additional","affiliation":[{"name":"Department of Audiology Sahlgrenska University Hospital Department of Audiology University of Gothenburg Gothenburg"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,3]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"99","article-title":"Unexpected ear disease in infants with cleft palate","volume":"4","author":"Stool SE","year":"1967","journal-title":"Cleft Palate J"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.44.1.35"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.07.015"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1258\/0022215011907668"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1975.00780390019005"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(88)90066-3"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1992.tb01827.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(03)00098-3"},{"issue":"2","key":"e_1_2_7_10_1","first-page":"95","article-title":"The middle ear of cleft palate patients in their early teens: a literature study and preliminary file study","volume":"4","author":"Timmermans K","year":"2006","journal-title":"B\u2010ENT"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110001110"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1597\/03-138.1"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199709001-00003"},{"key":"e_1_2_7_14_1","first-page":"93","article-title":"Roentgenographic evaluation of eustachian tube function in infants with cleft and normal palates","volume":"9","author":"Bluestone CD","year":"1972","journal-title":"Cleft Palate J"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(1996)033<0127:COTHHO>2.3.CO;2"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199203000-00004"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(96)01412-7"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(1990)027<0036:HLACPT>2.3.CO;2"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000172207.59888.a2"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-199602000-00001"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aud.0000224727.45342.e9"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-200006000-00003"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.5.1412"},{"key":"e_1_2_7_24_1","series-title":"Assessment of medical care of children: Contrasts in Health Status","author":"Kessner DM","year":"1974"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/00034894800890S305"},{"key":"e_1_2_7_26_1","volume-title":"Otitis Media With Effusion In Children: The Dunedin Study. 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