{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T13:29:23Z","timestamp":1780061363858,"version":"3.54.0"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,4,2]],"date-time":"2013-04-02T00:00:00Z","timestamp":1364860800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>Traumatic optic neuropathy (TON) is an important cause of severe visual impairment following blunt or penetrating head trauma. Treatment options include steroids, decompression, or both. Studies have failed to show a clear benefit for either steroids or surgery or a combined therapy. This study describes the visual outcome in surgically managed patients with or without steroid treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a retrospective chart review we included patients (n = 42) with TON who were managed with optic nerve decompression surgery with or without steroids. Comparison of initial and final visual acuity was the primary outcome parameter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 42 consecutive patients, steroids were used in 21 cases (50%). Ten patients received a high\u2010dose systemic regimen of more than 500 mg methylprednisolone initial dose, and 11 patients were treated with a lower dose. The overall visual improvement rate was 33%, no change was noted in 50%, and no outcome data were available in 17%. The visual improvement rate of patients treated with decompression surgery and steroids was lower (29%, 6 of 21) than those treated with surgery alone (53%, 8 of 15). Comparing both groups, additional steroids had no beneficial effect on the visual outcome (<jats:italic>P<\/jats:italic> = .97). There was no case with a deterioration of visual function due to therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients with traumatic optic neuropathy who were treated with optic nerve decompression surgery, steroids had no beneficial effect on the visual outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2c.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.23845","type":"journal-article","created":{"date-parts":[[2013,4,2]],"date-time":"2013-04-02T18:22:07Z","timestamp":1364926927000},"page":"1082-1086","source":"Crossref","is-referenced-by-count":45,"title":["The effect of steroids in combination With optic nerve decompression surgery in traumatic optic neuropathy"],"prefix":"10.1002","volume":"123","author":[{"given":"Thorsten","family":"Ropposch","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Paracelsus Medical University Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Steger","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry Paracelsus Medical University Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cem","family":"Me\u00e7o","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Paracelsus Medical University Salzburg Austria"},{"name":"Department of Otorhinolaryngology Ankara University Medical School Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Emesz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry Paracelsus Medical University Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Reitsamer","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry Paracelsus Medical University Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Rasp","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Paracelsus Medical University Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Moser","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Paracelsus Medical University Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,2]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"125","article-title":"Indirect traumatic optic neuropathy\u2014visual outcome of operative and nonoperative cases","volume":"30","author":"Fujitani T","year":"1986","journal-title":"Jpn J Ophthalmol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)00707-1"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(94)90145-7"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.11.1203"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.76.6.349"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199806000-00016"},{"key":"e_1_2_6_8_1","first-page":"CD006032","article-title":"Steroids for traumatic optic neuropathy","volume":"17","author":"Yu\u2010Wai\u2010Man P","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.106007"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17188-2"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002341-200109000-00005"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.74.2.246"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00041327-200403000-00003"},{"key":"e_1_2_6_14_1","first-page":"CD005024","article-title":"Surgery for traumatic optic neuropathy","volume":"19","author":"Yu\u2010Wai\u2010Man P","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_15_1","first-page":"CD006032","article-title":"Steroids for traumatic optic neuropathy","volume":"19","author":"Yu\u2010Wai\u2010Man P","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007010050262"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01400526"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/66.2.140"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-006-0441-0"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.23845","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.23845","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.23845","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.23845","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T12:21:35Z","timestamp":1692534095000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.23845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,2]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1002\/lary.23845"],"URL":"https:\/\/doi.org\/10.1002\/lary.23845","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,2]]}}}