{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T01:00:23Z","timestamp":1790038823287,"version":"4.0.1"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,12,17]],"date-time":"2013-12-17T00:00:00Z","timestamp":1387238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>In sialendoscopy, stents are often used to keep the salivary duct open after surgery. These stents need to be removed. Recently, our group developed a new starch\u2010based shape\u2010memory material that is a widespread degradable polymer. Such a device could be manufactured into a deployable resorbable stent to keep the salivary duct open before in situ degradation. An experimental test was performed to establish a methodology and to evaluate the feasibility of the starch stent implantation in an animal model with clinical equipment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Evaluation of different formulations\u2014potato and high amylose content maize starch without and with plasticizer\u2014with laboratory bench\u2010top testing and in vivo evaluation in a large\u2010animal model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Starch\u2010based stents were manufactured. They were evaluated for their shape\u2010memory properties (water, 37\u00b0C) and their degradability in simulated saliva in both static and flow conditions mimicking salivary flow in the submandibular duct. A pilot study of stent implantation was then performed in vivo in a large\u2010animal model to assess that the stent dimensions were consistent for implantation in the submandibular duct.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Stents made from plasticized starch had the required shape\u2010memory properties to be used as self\u2010deploying stents. However, starch\u2010based stents were rapidly hydrolyzed in simulated saliva. Stents could be directly inserted in the dilated salivary duct in a pig model without harming the epithelium.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Shape\u2010memory stents with suitable geometry for sialendoscopic surgical procedure can be fabricated and inserted in the submandibular duct. Starch\u2010based stents can be used in other pathologies with less \u03b1\u2010amylase content in the surrounding medium.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>NA. <jats:italic>Laryngoscope<\/jats:italic>, 124:875\u2013881, 2014<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.24380","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T14:23:33Z","timestamp":1381242213000},"page":"875-881","source":"Crossref","is-referenced-by-count":36,"title":["A resorbable shape\u2010memory starch\u2010based stent for the treatment of salivary ducts under sialendoscopic surgery"],"prefix":"10.1002","volume":"124","author":[{"given":"Anne","family":"Beilvert","sequence":"first","affiliation":[{"name":"INRA UR1268, Unit\u00e9 Biopolym\u00e8res Interactions et Assemblages Nantes, France"},{"name":"European Sialendoscopy Training Center Clinique G\u00e9n\u00e9rale Beaulieu Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Faure","sequence":"additional","affiliation":[{"name":"D\u00e9partement d'ORL et Chirurgie Cervico\u2010Maxillo\u2010Faciale H\u00f4pital \u00c9douard Herriot Lyon, France"},{"name":"Bioengineering for Cardiovascular and Therapy Team Universit\u00e9 Paris 13 Sorbonne Paris Cit\u00e9, INSERM, U698 Paris, France"},{"name":"Institut Universitaire de Technologie de Saint\u2010Denis Saint\u2010Denis, France"},{"name":"Institut Galil\u00e9e Villetaneuse, France"},{"name":"H\u00f4pital Sainte Musse Service d'ORL et de Chirurgie Cervico\u2010Faciale Toulon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Meddahi\u2010Pell\u00e9","sequence":"additional","affiliation":[{"name":"Bioengineering for Cardiovascular and Therapy Team Universit\u00e9 Paris 13 Sorbonne Paris Cit\u00e9, INSERM, U698 Paris, France"},{"name":"Institut Universitaire de Technologie de Saint\u2010Denis Saint\u2010Denis, France"},{"name":"Institut Galil\u00e9e Villetaneuse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Chaunier","sequence":"additional","affiliation":[{"name":"INRA UR1268, Unit\u00e9 Biopolym\u00e8res Interactions et Assemblages Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Guilois","sequence":"additional","affiliation":[{"name":"INRA UR1268, Unit\u00e9 Biopolym\u00e8res Interactions et Assemblages Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Chaubet","sequence":"additional","affiliation":[{"name":"Institut Galil\u00e9e Villetaneuse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Lourdin","sequence":"additional","affiliation":[{"name":"INRA UR1268, Unit\u00e9 Biopolym\u00e8res Interactions et Assemblages Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Bizeau","sequence":"additional","affiliation":[{"name":"H\u00f4pital Sainte Musse Service d'ORL et de Chirurgie Cervico\u2010Faciale Toulon France"},{"name":"European Sialendoscopy Training Center Clinique G\u00e9n\u00e9rale Beaulieu Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199910143411620"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.9.951"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2012.08.004"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2012.1618"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2012.856"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/star.200800074"},{"key":"e_1_2_7_8_1","unstructured":"LourdinD ChaunierL.Shape memory composition comprising starch. 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