{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:19:41Z","timestamp":1760217581819},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,10,22]],"date-time":"2013-10-22T00:00:00Z","timestamp":1382400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To describe the method of inserting a wedge\u2010shaped adjustable balloon implant (wABI) via a minithyrotomy for medialization thyroplasty and evaluate its effect on a range of phonatory parameters using the excised larynx bench apparatus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Repeated measures with each larynx serving as its own control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prototype wABI was deployed in six excised canine larynges of various sizes through a minithyrotomy and then filled with saline. Mucosal wave, aerodynamic, and acoustic parameters were measured for three conditions: normal, vocal fold paralysis, and paralysis with the wABI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Phonation threshold pressure (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), flow (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), and power (<jats:italic>P<\/jats:italic>\u2009=\u2009.002) were significantly lower for wABI compared to paralysis trials; values did not differ significantly from normal trials. Percent jitter (<jats:italic>P<\/jats:italic>\u2009=\u2009.002) and percent shimmer (<jats:italic>P<\/jats:italic>\u2009=\u2009.007) were also significantly decreased compared to the paralysis condition, and values were not significantly different compared to normal. The mucosal wave was preserved after insertion of the wABI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Effective vocal fold medialization with preservation of the mucosal wave was observed with the wABI in this preliminary excised larynx experiment. The wABI offers the potential for a minimally invasive insertion in addition to postoperative adjustability. Further studies in living animals and humans are warranted to evaluate clinical utility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>NA. <jats:italic>Laryngoscope<\/jats:italic>, 124:942\u2013949, 2014<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.24409","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T01:37:17Z","timestamp":1381541837000},"page":"942-949","source":"Crossref","is-referenced-by-count":6,"title":["Excised larynx evaluation of wedge\u2010shaped adjustable balloon implant for minimally invasive type I thyroplasty"],"prefix":"10.1002","volume":"124","author":[{"given":"Matthew R.","family":"Hoffman","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2013Head and Neck Surgery University of Wisconsin\u2013Madison School of Medicine and Public Health Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin E.","family":"Devine","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2013Head and Neck Surgery University of Wisconsin\u2013Madison School of Medicine and Public Health Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy M.","family":"McCulloch","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2013Head and Neck Surgery University of Wisconsin\u2013Madison School of Medicine and Public Health Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack J.","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology\u2013Head and Neck Surgery University of Wisconsin\u2013Madison School of Medicine and Public Health Madison Wisconsin U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(05)80323-6"},{"key":"e_1_2_7_3_1","first-page":"1265","article-title":"Plastic surgery on the thyroid cartilage for treatment of unilateral vocal fold paralysis","volume":"43","author":"Payr E","year":"1915","journal-title":"Dtsch Med Wochenschr"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487409126379"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198607000-00004"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949910800112"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949810700512"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199811000-00020"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)31073-2"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0892-1997(03)00080-8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459980112400603"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21431"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199308000-00008"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949810700602"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20122"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e3181373a4f"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200005000-00037"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1044\/1092-4388(2010\/10-0105)"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318177096f"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.24409","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.24409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T00:37:21Z","timestamp":1696379841000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.24409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,22]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1002\/lary.24409"],"URL":"https:\/\/doi.org\/10.1002\/lary.24409","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,22]]}}}