{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:59:54Z","timestamp":1781657994755,"version":"3.54.5"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,11,13]],"date-time":"2013-11-13T00:00:00Z","timestamp":1384300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To determine the long\u2010term results of frontal sinus drillout (also known as modified Lothrop procedure) for the treatment of advanced frontal sinus disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The records of patients who underwent frontal sinus drillout by a single surgeon at an academic medical center from June 1995 through November 2011 were reviewed. Patient demographics and perioperative clinical findings were analyzed for their impact on surgical outcome. Failure was defined as restenosis of the frontal drainage pathways, necessitating additional frontal sinus surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 204 patients underwent frontal drillout surgery (143 bilateral procedures) over the 16\u2010year period. Mean follow\u2010up was 10.2 years (range 0.9\u201317 years). Symptomatic re\u2010obstruction of the frontal sinus requiring revision surgery occurred in 61 (29.9%) patients. Drillouts performed for a diagnosis of mucocele or tumor had significantly higher failure rate (38.9%, odds ratio [OR]\u2009=\u20092.9, <jats:italic>P<\/jats:italic>\u2009=\u20090.022 and 58.3%, OR\u2009=\u20095.3, <jats:italic>P<\/jats:italic>\u2009=\u20090.020, respectively). The majority of surgical failures (61%) occurred within 2 years of surgery, but delayed failures were observed up to 12 years after drillout. Clinical outcome did not correlate with a history of smoking, asthma, nasal allergy, aspirin sensitivity, prior sinus surgery, nasal polyposis, or the presence of eosinophilic mucin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For the majority of patients who undergo frontal sinus drillout, patency of the frontal sinus outflow tract appears to be maintained for more than a decade; nevertheless, almost one\u2010third of patients who undergo this procedure will ultimately require additional frontal sinus surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4. <jats:italic>Laryngoscope<\/jats:italic>, 124:1066\u20131070, 2014<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.24422","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T01:41:13Z","timestamp":1381542073000},"page":"1066-1070","source":"Crossref","is-referenced-by-count":60,"title":["Frontal sinus drillout (modified Lothrop procedure): Long\u2010term results in 204 patients"],"prefix":"10.1002","volume":"124","author":[{"given":"Jonathan Y.","family":"Ting","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Indiana University School of Medicine Indianapolis Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Cedars Sinai Medical Center Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"Metson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary, Harvard Medical School Boston Massachusetts U.S.A."},{"name":"Department of Otology and Laryngology Massachusetts Eye and Ear Infirmary, Harvard Medical School Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(03)00153-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1043-1810(10)80087-9"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949410301205"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989570080-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2500\/105065897781446784"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20565"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.8.854"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/194589240201600206"},{"issue":"17","key":"e_1_2_6_10_1","first-page":"3","article-title":"Type III frontal sinusotomy: surgical technique, indications, outcomes, a multi\u2010university retrospective study of 120 cases","volume":"7","author":"Eloy P","year":"2011","journal-title":"B\u2010ENT"},{"key":"e_1_2_6_11_1","first-page":"195","article-title":"Long terms results of Draf type III (modified endoscopic Lothrop) frontal sinus drainage procedure in 122 patients: a single centre experience","volume":"49","author":"Georgalas C","year":"2011","journal-title":"Rhinology"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31806865be"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2500\/105065898780182444"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2011.10.002"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812441570"}],"container-title":["The 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