{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:01:59Z","timestamp":1779235319511,"version":"3.51.4"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,9,19]],"date-time":"2014-09-19T00:00:00Z","timestamp":1411084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To determine factors influencing sleep time with oxygen saturation below 90% (ST<jats:sub>90<\/jats:sub>) in a population referred to a tertiary sleep center for assessment of possible sleep\u2010disordered breathing (SDB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective review of demographic and polysomnographic data of 731 consecutive patients with suspected SDB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Bivariate correlation analyses were performed, and Spearman rho coefficients were calculated. Variables with a marginal association with ST<jats:sub>90<\/jats:sub> (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05) in the bivariate analysis were included into the multiple regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The distributions of SDB were as follows: normal\/simple snoring, 18.2%; mild obstructive sleep apnea (OSA), 25.6%; moderate OSA, 17.4%; and severe OSA, 38.9%. The univariate analysis revealed a significant correlation between ST<jats:sub>90<\/jats:sub> and age (<jats:italic>r<\/jats:italic>\u2009=\u20090.204), body mass index (BMI) (<jats:italic>r<\/jats:italic>\u2009=\u20090.440), arousal index (<jats:italic>r<\/jats:italic>\u2009=\u20090.754), apnea\u2010hypopnea index (AHI) (<jats:italic>r<\/jats:italic>\u2009=\u20090.761), mean oxygen saturation (SaO<jats:sub>2<\/jats:sub>) (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.506), and mean O<jats:sub>2<\/jats:sub> desaturation (<jats:italic>r<\/jats:italic>\u2009=\u20090.858) (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001 for all parameters). In multiple regression analysis, age (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), BMI (<jats:italic>P<\/jats:italic>\u2009=\u2009.040), male gender (<jats:italic>P<\/jats:italic>\u2009=\u2009.001), AHI (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), mean SaO<jats:sub>2<\/jats:sub> (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), and mean O<jats:sub>2<\/jats:sub> desaturation (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) were found to be independent parameters influencing ST<jats:sub>90<\/jats:sub>. Furthermore, these parameters explained a significant proportion of variance in ST<jats:sub>90<\/jats:sub> (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.794, <jats:italic>F<\/jats:italic> (6, 729)\u2009=\u2009464.65, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). Although there was a strong correlation between AHI and ST<jats:sub>90<\/jats:sub> (<jats:italic>r<\/jats:italic>\u2009=\u20090.76, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), a large variation of ST<jats:sub>90<\/jats:sub> values was observed, especially within the severe OSA group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The study results provide supporting evidence that patients with similar AHI may have quite different values of ST<jats:sub>90,<\/jats:sub> and thereby hypoxia. The stratification of patients with OSA according to AHI combined with ST<jats:sub>90<\/jats:sub> may allow better identification of prognostic information.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 125:1008\u20131012, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.24942","type":"journal-article","created":{"date-parts":[[2014,9,19]],"date-time":"2014-09-19T08:07:16Z","timestamp":1411114036000},"page":"1008-1012","source":"Crossref","is-referenced-by-count":18,"title":["Factors influencing sleep time with oxygen saturation below 90% in sleep\u2010disordered breathing"],"prefix":"10.1002","volume":"125","author":[{"given":"Asli","family":"Bostanci","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Akdeniz University School of Medicine Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Turhan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Akdeniz University School of Medicine Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selen","family":"Bozkurt","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Medical Informatics Akdeniz University School of Medicine Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60734-5"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1237122"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.2.2010012"},{"key":"e_1_2_6_5_1","volume-title":"The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications","author":"Iber C","year":"2007"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11517-013-1039-4"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00009506"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000202980"},{"key":"e_1_2_6_9_1","first-page":"3115","article-title":"Clinical value of TS90% in evaluation of hypoxemia in patients with obstructive sleep apnea\/hypoventilation syndrome [in Chinese]","volume":"85","author":"Li JR","year":"2005","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"e_1_2_6_10_1","first-page":"825","article-title":"Correlations between the duration and frequency of sleep apnea episode and hypoxemia in patients with obstructive sleep apnea syndrome [in Chinese]","volume":"44","author":"Li Q","year":"2009","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3044-0"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24510"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.5.7582313"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2011.02082.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200404-510OC"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1053\/smrv.2002.0261"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1515\/BC.2004.015"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2001.90.4.1593"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.24942","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.24942","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T06:41:10Z","timestamp":1696401670000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.24942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,19]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1002\/lary.24942"],"URL":"https:\/\/doi.org\/10.1002\/lary.24942","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,19]]}}}