{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:48:28Z","timestamp":1786978108806,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,24]],"date-time":"2014-10-24T00:00:00Z","timestamp":1414108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives\/Hypothesis<\/jats:title>\n                    <jats:p>We reviewed our experience with the use of transoral robotic surgery (TORS) for base of tongue (BOT) reduction either alone or as part of multilevel strategy in the treatment of obstructive sleep apnea\/hypopnea syndrome (OSAHS) in order to identify clinical characteristics that may be associated with surgical response.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Case series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between June 2010 and May 2014, BOT reduction via TORS\u2009\u00b1\u2009partial epiglottectomy\u2009\u00b1\u2009uvulopalatopharyngoplasty were performed on 72 patients with OSAHS. Thirty\u2010nine patients (15 females and 24 males) with complete preoperative and postoperative clinical information including polysomnograms were included in this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean apnea\u2010hypopnea index (AHI) was 43.9\u2009\u00b1\u200932.3 preoperatively and 21.9\u2009\u00b1\u200923.5 postoperatively and reflected a statistically significant (P\u2009&lt;\u20090.001) AHI reduction of 50.9%\u2009\u00b1\u200938.1%. Statistical significant reduction in daytime somnolence, as measured by Epworth Sleepiness Scale (15.6\u2009\u00b1\u20095.4 preoperatively vs. 5.7\u2009\u00b1\u20094.3 postoperatively; P\u2009&lt;\u20090.001), was also achieved. No statistical significant difference was found between preoperative and postoperative body mass index (BMI) (32.9\u2009\u00b1\u20097.0 vs. 32.4\u2009\u00b1\u20097.3;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.270). Surgical response, as defined by\u2009&gt;\u200950% reduction in AHI and final AHI\u2009&lt;\u200915 with resolution of daytime somnolence, was achieved in 21 patients (53.8%). Clinical characteristics found to be significantly different between the responders and nonresponders were BMI, AHI, and lateral velopharyngeal collapse. Patients with BMI\u2009&lt;\u200930, AHI\u2009&lt;\u200960, or absence of lateral velopharyngeal collapse have excellent surgical response rate of 88.2%, 67.9%, or 66.7%, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We identified three clinical characteristics associated with increased surgical response rate. This finding may be useful for patient selection and counseling prior to surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      4.\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 125:1013\u20131020, 2015\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.24970","type":"journal-article","created":{"date-parts":[[2014,10,24]],"date-time":"2014-10-24T04:14:12Z","timestamp":1414124052000},"page":"1013-1020","source":"Crossref","is-referenced-by-count":59,"title":["Transoral robotic surgery for treatment of obstructive sleep apnea: Factors predicting surgical response"],"prefix":"10.1002","volume":"125","author":[{"given":"Ho\u2010Sheng","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Wayne State University and Karmanos Cancer Institute Detroit Michigan U.S.A"},{"name":"Department of Surgery Wayne State University Detroit Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A.","family":"Rowley","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Critical Care and Sleep Medicine Department of Medicine Wayne State University Detroit Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam J.","family":"Folbe","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Wayne State University and Karmanos Cancer Institute Detroit Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George H.","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Wayne State University and Karmanos Cancer Institute Detroit Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Safwan","family":"Badr","sequence":"additional","affiliation":[{"name":"Department of Medicine John D. Dingell VA Medical Center Detroit Michigan U.S.A"},{"name":"Division of Pulmonary Critical Care and Sleep Medicine Department of Medicine Wayne State University Detroit Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Biostatistics Core Karmanos Cancer Institute Department of Oncology Wayne State University Detroit Michigan U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)71141-7"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.14.1906"},{"key":"e_1_2_6_4_1","first-page":"1071","article-title":"Sleep disordered breathing and mortality: eighteen\u2010year follow\u2010up of the Wisconsin sleep cohort","volume":"31","author":"Young T","year":"2008","journal-title":"Sleep"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000132"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/19.2.156"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/33.10.1396"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/smrv.2002.0242"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.191"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940711600104"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.12.1220"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000227184.90514.1a"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348941212101002"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21691"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811434262"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23913"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000360768"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200403000-00013"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000181464.11943.C4"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.4.435"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.2.206"},{"key":"e_1_2_6_22_1","volume-title":"The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology, and Technical Specifications","author":"Iber C","year":"2007"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2011.06.004"},{"key":"e_1_2_6_24_1","unstructured":"Medicare national coverage determinations. 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