{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:45:50Z","timestamp":1791243950875,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,24]],"date-time":"2014-10-24T00:00:00Z","timestamp":1414108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To confirm the value of using laryngeal electromyography (LEMG) to predict the long\u2010term prognosis of unilateral vocal fold paralysis (UVFP), and elucidate the adequate timing of LEMG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective cohort prognosis study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The LEMG data of 84 patients with UVFP were prospectively collected, and 81 patients received follow\u2010up at least 6 months after symptom onset. If the paralyzed vocal fold had &lt;20% recruitment reduction during phonation compared to the normal vocal fold signals, and absence of fibrillation when the patient was silent, the prognosis was considered to be good (negative finding). Otherwise, the prognosis was considered to be poor (positive finding). The association between UVFP outcome and LEMG prognostic rules and the accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of LEMG were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean duration of LEMG after symptom onset was 3.7 months, and follow\u2010up after symptoms onset was 18.4 months. Sixty\u2010six of 71 patients with a positive finding had persistent UVFP; four of 10 patients with a negative finding recovered vocal fold motion. LEMG results were significantly associated with the outcome of UVFP (<jats:italic>P<\/jats:italic>\u2009=\u2009.007). The overall accuracy, sensitivity, specificity, PPV, and NPV of LEMG were 86.4%, 91.7%, 44.4%, 93.0%, and 40.0%, respectively. When LEMG was done more than 2 months after symptom onset, the PPV was 97.9%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>LEMG has a high PPV in predicting the long\u2010term outcome of UVFP patients with poor prognosis. Permanent laryngeal framework surgery is feasible if patients have positive findings at least 2 months after symptom onset.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>1b <jats:italic>Laryngoscope<\/jats:italic>, 125:898\u2013903, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.24980","type":"journal-article","created":{"date-parts":[[2014,10,24]],"date-time":"2014-10-24T08:44:45Z","timestamp":1414140285000},"page":"898-903","source":"Crossref","is-referenced-by-count":41,"title":["Laryngeal electromyography and prognosis of unilateral vocal fold paralysis\u2014A long\u2010term prospective study"],"prefix":"10.1002","volume":"125","author":[{"given":"Chen\u2010Chi","family":"Wang","sequence":"first","affiliation":[{"name":"School of Medicine, National Yang\u2010Ming University Taipei Taiwan"},{"name":"School of Speech Language Pathology &amp; Audiology, Chung\u2010Shan Medical University Taichung Taiwan"},{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Hong","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Neurology Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"De Virgilio","sequence":"additional","affiliation":[{"name":"Department of Sensory Organs ENT Section, Sapienza University of Rome Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong\u2010San","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Taichung Veterans General Hospital Taichung Taiwan"},{"name":"School of Medicine, Chung\u2010Shan Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsiu\u2010Chin","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching\u2010Ping","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Speech Language Pathology &amp; Audiology, Chung\u2010Shan Medical University Taichung Taiwan"},{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shang\u2010Heng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih\u2010An","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Medicine, National Yang\u2010Ming University Taipei Taiwan"},{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(83)80001-7"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1622.1999.01613.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2012.06.011"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/67.3.178"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.4.380"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22354"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.01.026"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.04.003"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-012-2036-1"},{"key":"e_1_2_7_11_1","article-title":"Laryngeal electromyography\u2010guided hyaluronic acid vocal fold injection for unilateral vocal fold paralysis\u2014a prospective long term follow up outcome report","author":"Wang CC","journal-title":"JAMA Otolaryngol Head Neck Surg."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-012-2211-4"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/66.4.237"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948909800201"},{"key":"e_1_2_7_15_1","first-page":"232","volume-title":"Neurolaryngology: Recent Advances","author":"Hirano M","year":"1987"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21046"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21884"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.2.155"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880160917"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940010900405"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(05)80323-6"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20629"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.24980","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.24980","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T06:42:33Z","timestamp":1696401753000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.24980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,24]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1002\/lary.24980"],"URL":"https:\/\/doi.org\/10.1002\/lary.24980","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,24]]}}}