{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:42:16Z","timestamp":1792662136394,"version":"4.5.0"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,11,24]],"date-time":"2014-11-24T00:00:00Z","timestamp":1416787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Middle ear surgery increasingly employs endoscopes as an adjunct to or replacement for the operative microscope. We provide a systematic review of endoscope applications in middle ear surgery with an emphasis on outcomes, including the need for conversion to microscope, audiometric findings, length of follow\u2010up, as well as disease\u2010specific outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>PubMed, Embase, and Cochrane CENTRAL database.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A literature review was performed using the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analysis recommendations. Articles were categorized based on study design, indication, and use of an endoscope either as an adjunct to or as a replacement for a microscope. Qualitative and descriptive analyses of studies and outcomes data were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One\u2010hundred three articles met inclusion and exclusion criteria. Of the identified articles, 38 provided outcomes data. The majority of these studies were moderate quality, retrospective, case\u2010series reports. The indications for use of the endoscope were broad, with the most common being resection of cholesteatoma. In cholesteatoma surgery, endoscope approaches routinely identified residual cholesteatoma in primary and second\u2010look cases. Other outcomes, including robust audiometric data, operating room times, wound healing, and quality of life surveys were not well described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Endoscopes have consistently been used as an adjunct to the microscope to improve visualization of the tympanic cavity. Recent reports utilize the endoscope exclusively during surgical dissection; however, data comparing patient outcomes following the use of an endoscope to a microscope are lacking. Areas in need of additional research are highlighted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      NA\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 125:1205\u20131214, 2015\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.25048","type":"journal-article","created":{"date-parts":[[2014,11,24]],"date-time":"2014-11-24T01:55:59Z","timestamp":1416794159000},"page":"1205-1214","source":"Crossref","is-referenced-by-count":172,"title":["Systematic review of outcomes following observational and operative endoscopic middle ear surgery"],"prefix":"10.1002","volume":"125","author":[{"given":"Elliott D.","family":"Kozin","sequence":"first","affiliation":[{"name":"Department of Otology and Laryngology Harvard Medical School, Boston, Massachusetts Boston Massachusetts U.S.A"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn","family":"Gulati","sequence":"additional","affiliation":[{"name":"Department of Otology and Laryngology Harvard Medical School, Boston, Massachusetts Boston Massachusetts U.S.A"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyson B.","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Department of Otology and Laryngology Harvard Medical School, Boston, Massachusetts Boston Massachusetts U.S.A"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashton E.","family":"Lehmann","sequence":"additional","affiliation":[{"name":"Department of Otology and Laryngology Harvard Medical School, Boston, Massachusetts Boston Massachusetts U.S.A"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron K.","family":"Remenschneider","sequence":"additional","affiliation":[{"name":"Department of Otology and Laryngology Harvard Medical School, Boston, Massachusetts Boston Massachusetts U.S.A"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas D.","family":"Landegger","sequence":"additional","affiliation":[{"name":"Department of Otology and Laryngology Harvard Medical School, Boston, Massachusetts Boston Massachusetts U.S.A"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Otology and Laryngology Harvard Medical School, Boston, Massachusetts Boston Massachusetts U.S.A"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otology and Laryngology Harvard Medical School, Boston, Massachusetts Boston Massachusetts U.S.A"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Infirmary Boston Massachusetts U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1967.00760040389009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/014556139407300708"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2009.07.010"},{"key":"e_1_2_7_5_1","article-title":"Concept, design and development of innovative endoscope holder system for endoscopic otolaryngological surgeries [published online ahead of print June 18, 2014]","author":"Khan M","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199602000-00020"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24666"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988209000406"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1990.01870100080017"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100126611"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199308000-00021"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1995.01890080038007"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949910800913"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199907000-00002"},{"key":"e_1_2_7_15_1","first-page":"153","article-title":"Results of endoscopic middle ear surgery for cholesteatoma treatment: a systematic review","volume":"34","author":"Presutti L","year":"2014","journal-title":"Acta Otolaryngol Ital"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2009.06.006"},{"key":"e_1_2_7_17_1","unstructured":"OCEBM Levels of Evidence Working Group. The Oxford levels of evidence. Available at:http:\/\/www.cebm.net\/ocebm\u2010levels\u2010of\u2010evidence. Accessed June 1 2015."},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014\u20100323"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.328.7454.1490"},{"key":"e_1_2_7_20_1","first-page":"158","article-title":"Surgery of sinus tympani cholesteatoma: endoscopic necessity","volume":"5","author":"Badr\u2010el\u2010Dine M","year":"2009","journal-title":"Int Adv Otol"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24633"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199710000-00009"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e318188e8d7"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59980301577-8"},{"key":"e_1_2_7_25_1","first-page":"158","article-title":"Endoscope\u2010assisted ear surgery","volume":"16","author":"Bottrill I","year":"1995","journal-title":"Am J Otol"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1258\/0022215011909765"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2012.10.004"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200407000-00005"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215107009346"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480802468187"},{"key":"e_1_2_7_31_1","first-page":"544","article-title":"Endoscopic management of acquired cholesteatoma","volume":"18","author":"Tarabichi M","year":"1997","journal-title":"Am J Otol"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59980070017-9"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182096b39"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010014\u20103214\u20100"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949910800106"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1159\/000055759"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.04.013"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24144"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010014\u20102995\u20105"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2490-4"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000510"},{"key":"e_1_2_7_42_1","first-page":"481","article-title":"Endoscopic management of acquired cholesteatoma: our experience","volume":"37","author":"Presutti L","year":"2008","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200209000-00004"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182171007"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.25048","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.25048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T15:10:21Z","timestamp":1696345821000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.25048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,24]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1002\/lary.25048"],"URL":"https:\/\/doi.org\/10.1002\/lary.25048","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,24]]}}}