{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T15:14:49Z","timestamp":1725981289798},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,11,25]],"date-time":"2014-11-25T00:00:00Z","timestamp":1416873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>This cadaveric study analyzes the endoscopic endonasal anatomy of the ophthalmic division of the trigeminal nerve (V<jats:sub>1<\/jats:sub>), from the middle fossa to its orbital entry via the superior orbital fissure. Anatomical relationships with the surrounding cranial nerves and blood vessels are described, with emphasis on their clinical correlation during surgery in this region. Our objective was to describe the anatomical relationships of the ophthalmic division of the trigeminal nerve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Cadaveric study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty middle cranial fossae, in adult human cadaveric specimens, were dissected endonasally under direct endoscopic visualization. During the dissection, we noted the relationships of the V<jats:sub>1<\/jats:sub> nerve with the other trigeminal branches, as well as with the oculomotor and trochlear nerves, the paraclival and cavernous portions of the internal carotid artery, and the superior orbital fissure (SOF).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The V<jats:sub>1<\/jats:sub> nerve is the most superior trigeminal branch and runs upward and obliquely, along the middle portion of the lateral wall of the cavernous sinus. The V<jats:sub>1<\/jats:sub> nerve joins the oculomotor and trochlear nerves to exit the cavernous sinus and enter the orbit through the SOF. Ten percent of the specimens displayed the trochlear nerve running along as a mate of the V<jats:sub>1<\/jats:sub> nerve. The V<jats:sub>1<\/jats:sub> nerve borders two key triangles in the lateral wall of the cavernous sinus, and the Parkinson's and anteromedial triangles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this study, the V<jats:sub>1<\/jats:sub> nerve was a constant and reliable landmark, thus allowing the identification of the anteromedial triangle. This potential space can serve as an adequate window to access the temporal lobe. Knowledge of this anatomy is essential when planning and executing endonasal surgery in this region.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>NA <jats:italic>Laryngoscope<\/jats:italic>, 125:1284\u20131290, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.25050","type":"journal-article","created":{"date-parts":[[2014,11,25]],"date-time":"2014-11-25T20:06:57Z","timestamp":1416946017000},"page":"1284-1290","source":"Crossref","is-referenced-by-count":7,"title":["Endoscopic endonasal anatomical study of the cavernous sinus segment of the ophthalmic nerve"],"prefix":"10.1002","volume":"125","author":[{"given":"Ricardo L. L.","family":"Dolci","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Wexner Medical Center at The Ohio State University Columbus Ohio U.S.A"},{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Santa Casa de Miseric\u00f3rida de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo L.","family":"Carrau","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Wexner Medical Center at The Ohio State University Columbus Ohio U.S.A"},{"name":"Department of Neurosurgery Wexner Medical Center at The Ohio State University Columbus Ohio U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lamia","family":"Buohliqah","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Wexner Medical Center at The Ohio State University Columbus Ohio U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Zoli","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Wexner Medical Center at The Ohio State University Columbus Ohio U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo M.","family":"Mesquita Filho","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Wexner Medical Center at The Ohio State University Columbus Ohio U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo R.","family":"Lazarini","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Santa Casa de Miseric\u00f3rida de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leo F. 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