{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T04:44:14Z","timestamp":1770439454865,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,4,17]],"date-time":"2015-04-17T00:00:00Z","timestamp":1429228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To quantitatively measure volumetric changes in upper airway soft tissue structures using magnetic resonance imaging (MRI) pre\u2010 and post transoral robotic surgery for obstructive sleep apnea (OSA\u2010TORS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective, nonrandomized, institutional board\u2010approved study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Apneics undergoing OSA\u2010TORS, which included bilateral posterior hemiglossectomy with limited pharyngectomy and uvulopalatopharyngoplasty, had upper airway MRIs pre\u2010 and postoperatively. Changes (percent and absolute values) in upper airway and surrounding soft tissue volumes were calculated. We assessed whether there were significant volumetric changes and if changes correlated with apnea\u2010hypopnea index (AHI) changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen MRIs and 18 polysomnograms were analyzed pre\u2010 and postoperation. Total airway volume increased by 19.4% (<jats:italic>P<\/jats:italic>\u2009=\u20090.030). Soft palate and tongue volumes decreased by 18.3% (<jats:italic>P<\/jats:italic>\u2009=\u20090.002) and 5.8% (<jats:italic>P<\/jats:italic>\u2009=\u20090.013), respectively. Retropalatal and total lateral wall volumes decreased by 49.8% (<jats:italic>P<\/jats:italic>\u2009=\u20090.0001) and 17.9% (<jats:italic>P<\/jats:italic>\u2009=\u20090.008), respectively. Changes in other structures were not significant. Eleven patients had surgical success, with a mean AHI decrease of 52.9; six were nonsuccesses with a mean AHI decrease of 4.5 (<jats:italic>P<\/jats:italic> =0.006). Decreased retropalatal lateral wall volume correlated with decreased AHI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Airway, tongue, soft palate, and lateral wall volumes change significantly after OSA\u2010TORS. Changes in the volume of the lateral walls correlated with changes in AHI. Volumetric upper airway MRI may be a helpful tool to better understand reasons for surgical success.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4. <jats:italic>Laryngoscope<\/jats:italic>, 125:1988\u20131995, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.25270","type":"journal-article","created":{"date-parts":[[2015,4,17]],"date-time":"2015-04-17T17:50:47Z","timestamp":1429293047000},"page":"1988-1995","source":"Crossref","is-referenced-by-count":33,"title":["Volumetric <scp>MRI<\/scp> analysis pre\u2010 and post\u2010Transoral robotic surgery for obstructive sleep apnea"],"prefix":"10.1002","volume":"125","author":[{"given":"Rebecca C.","family":"Chiffer","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Hospital of the University of Pennsylvania, University of Pennsylvania Medical Center Philadelphia Pennsylvania U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Schwab","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Sleep Medicine Pulmonary Allergy and Critical Care Division Penn Sleep Center University of Pennsylvania Medical Center Philadelphia Pennsylvania U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brendan T.","family":"Keenan","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania Division of Sleep Medicine Center for Sleep and Circadian Neurobiology University of Pennsylvania Medical Center Philadelphia Pennsylvania U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan C.","family":"Borek","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Hospital of the University of Pennsylvania, University of Pennsylvania Medical Center Philadelphia Pennsylvania U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erica R.","family":"Thaler","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania Medical Center Philadelphia Pennsylvania U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1586\/17476348.2.3.349"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2109080"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.5935\/1808-8694.20130139"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348941212101002"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21691"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811434262"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23913"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.5.7582313"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/148.5.1385"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200208-866OC"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.54.4.323"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23553"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.4238\/2014.June.17.7"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0b013e3182a0229a"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200009000-00029"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.25270","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.25270","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T02:14:08Z","timestamp":1696385648000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.25270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,17]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1002\/lary.25270"],"URL":"https:\/\/doi.org\/10.1002\/lary.25270","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,17]]}}}