{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T20:06:22Z","timestamp":1779912382008,"version":"3.53.1"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T00:00:00Z","timestamp":1435104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"crossref","award":["NSC 102-2314-B-182A-080"],"award-info":[{"award-number":["NSC 102-2314-B-182A-080"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"crossref","award":["NSC 103-2314-B-182A-056-MY2"],"award-info":[{"award-number":["NSC 103-2314-B-182A-056-MY2"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004606","name":"Chang Gung Medical Foundation","doi-asserted-by":"crossref","award":["CMRPG 3B1032"],"award-info":[{"award-number":["CMRPG 3B1032"]}],"id":[{"id":"10.13039\/501100004606","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004606","name":"Chang Gung Medical Foundation","doi-asserted-by":"crossref","award":["BMRP390021"],"award-info":[{"award-number":["BMRP390021"]}],"id":[{"id":"10.13039\/501100004606","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>Determination of superior laryngeal nerve (SLN) involvement in addition to recurrent laryngeal nerve (RLN) paralysis in patients with unilateral vocal fold paralysis (UVFP) relies on traditional, qualitative laryngeal electromyography (LEMG) examination. It is necessary to develop a quantitative measurement that reflects the degree of denervation of the cricothyroid (CT) muscle. The present study aimed to establish a standard quantitative assessment of CT function in patients with UVFP by measuring the turn frequency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case series study performed in an otolaryngology outpatient clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty healthy subjects and 103 patients with UVFP were recruited. The main outcome measures for the patients included acoustic analysis using traditional LEMG examination, quantitative LEMG analysis, and acoustic analysis based on fundamental frequency contours.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Acoustic reliability was examined in the healthy subjects, and the peak fundamental frequency in an upward glissando showed good test\u2013retest reliability, especially for the offset fundamental frequency. LEMG indicated that 33 patients had RLN and SLN lesions (RLN\u2009+\u2009SLN group) and 70 had only RLN lesions (RLN group). When patients produced a standard upward glissando sound, the peak turn frequency reflecting the recruitment of the CT muscle was significantly lower in the RLN\u2009+\u2009SLN group compared with the RLN group (406\u2009\u00b1\u2009256 vs. 778\u2009\u00b1\u2009238 Hz; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We conclude that quantitative measurement of the interference pattern when voicing a standard upward glissando sound may provide a feasible reflection of the degree of a SLN injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 125:2530\u20132535, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.25418","type":"journal-article","created":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T15:58:27Z","timestamp":1435161507000},"page":"2530-2535","source":"Crossref","is-referenced-by-count":18,"title":["Quantitative laryngeal electromyography assessment of cricothyroid function in patients with unilateral vocal fold paralysis"],"prefix":"10.1002","volume":"125","author":[{"given":"Tuan\u2010Jen","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan"},{"name":"School of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Cheng","family":"Pei","sequence":"additional","affiliation":[{"name":"School of Medicine Chang Gung University Taoyuan Taiwan"},{"name":"Department of Physical Medicine and Rehabilitation Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan"},{"name":"Healthy Aging Research Center Chang Gung University Taoyuan Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Jen","family":"Hsin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan"},{"name":"School of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan\u2010Ni","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan"},{"name":"School of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Ang","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan"},{"name":"School of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsueh\u2010Yu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan"},{"name":"School of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice M. K.","family":"Wong","sequence":"additional","affiliation":[{"name":"School of Medicine Chang Gung University Taoyuan Taiwan"},{"name":"Department of Physical Medicine and Rehabilitation Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan"},{"name":"Healthy Aging Research Center Chang Gung University Taoyuan Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24229"},{"key":"e_1_2_7_3_1","first-page":"463","article-title":"Contribution to the mutual functional relationships of the muscles of the larynx","volume":"18","author":"Grossman M","year":"1906","journal-title":"Arch Laryngol Rhinol"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016486409136945"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197010000-00001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/177340a0"},{"key":"e_1_2_7_7_1","first-page":"496","article-title":"Laryngeal electromyography \u2010 techniques, applications, and a review of personal experience","volume":"6","author":"Blair RL","year":"1977","journal-title":"J Otolaryngol"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487209128448"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1981.tb01547.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(03)00146-1"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.4.380"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21884"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22354"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21046"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489009125171"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000199743.99527.9F"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.1458024"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949610501002"},{"key":"e_1_2_7_19_1","first-page":"437","year":"1890","journal-title":"Wagner R. 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