{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T11:06:30Z","timestamp":1759057590662},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T00:00:00Z","timestamp":1435104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>The purpose of this study was to evaluate our patient\u2010reported and objective long\u2010term outcomes of patients treated for laryngotracheal stenosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010five patients were evaluated after a median follow\u2010up of 7 years after surgery. Follow\u2010up measurements consisted of pulmonary function testing, Bruce treadmill test, and Child Health Questionnaires (CHQ).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pulmonary function tests were available in 43 patients, and 30\/43 had abnormal forced expiratory volume in 1 second\/forced inspiratory volume in 1 second (FIV1), 25\/43 had abnormal FIV1\/maximum vital capacity, and 24\/43 had abnormal peak expiratory flow. One\u2010third of patients had reduced exercise tolerance. CHQ revealed significant positive correlations with pulmonary function results and exercise tolerance. Multivariate analysis showed that glottic involvement of the stenosis and the presence of comorbidities at time of surgery are the only factors for poor long\u2010term functional outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The majority of patients show deficits in pulmonary function and exercise tolerance related to lower scores of quality of life. Glottic involvement of the stenosis and the presence of comorbidities are the only significant factors for poor functional outcome. Long\u2010term multidisciplinary follow up is mandatory after surgery for laryngotracheal stenosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2B. <jats:italic>Laryngoscope<\/jats:italic>, 126:472\u2013477, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.25419","type":"journal-article","created":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T16:13:28Z","timestamp":1435162408000},"page":"472-477","source":"Crossref","is-referenced-by-count":7,"title":["Long\u2010term functional airway assessment after open airway surgery for laryngotracheal stenosis"],"prefix":"10.1002","volume":"126","author":[{"given":"Bas","family":"Pullens","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery Erasmus Medical Center, Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marielle W.","family":"Pijnenburg","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pediatric Pulmonology Erasmus Medical Center, Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans J.","family":"Hoeve","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery Erasmus Medical Center, Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rob J.","family":"Baatenburg de Jong","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery Erasmus Medical Center, Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinne M. P.","family":"Buysse","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Intensive Care Unit Erasmus Medical Center, Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marieke K.","family":"Timmerman","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery Erasmus Medical Center, Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc P.","family":"van der Schroeff","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Neck Surgery Erasmus Medical Center, Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koen F. M.","family":"Joosten","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Intensive Care Unit Erasmus Medical Center, Sophia Children's Hospital Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2012.01.006"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.109007"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(00)00360-8"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940111001204"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1007\/978-3-642-13535-4","volume-title":"Pediatric Airway Surgery\u2014Management of Laryngotracheal Stenosis in Infants and Children","author":"Monnier P","year":"2011"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-002-0526-2"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23824"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2000.00399.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812472435"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200311000-00028"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813510867"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24373"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.05.034"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200708-1248OC"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(73)90502-4"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.2009.00925.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(01)00411-5"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949210100602"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-012-2080-x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198808000-00012"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(93)90232-R"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2012-203079"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.25419","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.25419","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T06:45:16Z","timestamp":1695710716000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.25419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,24]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1002\/lary.25419"],"URL":"https:\/\/doi.org\/10.1002\/lary.25419","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,24]]}}}