{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:44:10Z","timestamp":1792791850274,"version":"4.5.0"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,11,24]],"date-time":"2015-11-24T00:00:00Z","timestamp":1448323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>Transoral laser microsurgery (TLM) continues to gain popularity as a treatment modality for early glottic cancer. Oncologic outcomes have been well\u2010defined, but there are little data to date describing functional outcomes accounting for stage of resection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed patient\u2010rated voice handicap and observer\u2010rated vocal quality of patients who underwent TLM for early glottic carcinoma. Patients were grouped by European Laryngological Society (ELS) resection type, and the data were combined for ELS type I\u2013III and compared with advanced resections (ELS IV\u2013VI). The Voice Handicap Index (VHI) was used for patient\u2010rated voice outcomes, and voice recordings were graded by two senior speech\u2010language pathologists. Voice recordings and VHI scores were taken preoperatively and at least 1 month postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No major complications were encountered. Six of 49 patients underwent repeat resection for suspicious findings with pathology, demonstrating moderate dysplasia in two cases, carcinoma in situ in two cases, and inflamed mucosa only in two cases. There was no significant difference in preoperative VHI scores or objective voice grades among patients who underwent limited (ELS I\u2013III) and those who required more advanced (ELS IV\u2013VI) resection. There was a significant improvement in VHI scores in patients after ELS type I to III resection, from 38.77 to 22.86 (<jats:italic>P<\/jats:italic>\u2009=\u2009.006). There was no significant difference between mean preoperative and postoperative perceptual evaluation scores in patients who underwent ELS type I, II, or III resections (62.25 and 64.32 respectively, <jats:italic>P<\/jats:italic>\u2009=\u2009.621).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients who undergo limited ELS resections can be assured of having a similar to improved voice after healing. Patients who undergo extended resections have poorer vocal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 126:405\u2013407, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.25442","type":"journal-article","created":{"date-parts":[[2015,11,24]],"date-time":"2015-11-24T07:32:27Z","timestamp":1448350347000},"page":"405-407","source":"Crossref","is-referenced-by-count":31,"title":["Subjective and objective voice outcomes after transoral laser microsurgery for early glottic cancer"],"prefix":"10.1002","volume":"126","author":[{"given":"Daniel S.","family":"Fink","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Louisiana State University Health Sciences Center New Orleans Louisiana U.S.A"},{"name":"Our Lady of the Lake Voice Center Baton Rouge Louisiana U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haley","family":"Sibley","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Louisiana State University Health Sciences Center New Orleans Louisiana U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melda","family":"Kunduk","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Louisiana State University Health Sciences Center New Orleans Louisiana U.S.A"},{"name":"Our Lady of the Lake Voice Center Baton Rouge Louisiana U.S.A"},{"name":"Department of Communication Sciences and Disorders Louisiana State University Baton Rouge Louisiana U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mell","family":"Schexnaildre","sequence":"additional","affiliation":[{"name":"Our Lady of the Lake Voice Center Baton Rouge Louisiana U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anagha","family":"Kakade","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Louisiana State University Health Sciences Center New Orleans Louisiana U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Collin","family":"Sutton","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Louisiana State University Health Sciences Center New Orleans Louisiana U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"McWhorter","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Louisiana State University Health Sciences Center New Orleans Louisiana U.S.A"},{"name":"Our Lady of the Lake Voice Center Baton Rouge Louisiana U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20181"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21027"},{"issue":"1","key":"e_1_2_6_4_1","first-page":"S49","article-title":"Functional outcomes and laryngectomy\u2010free survival after transoral CO(2) laser microsurgery for stage 1 and 2 glottic carcinoma","volume":"40","author":"Kujath M","year":"2011","journal-title":"J Otolaryngol Head Neck 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Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.25442","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.25442","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T06:43:57Z","timestamp":1695710637000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.25442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,24]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1002\/lary.25442"],"URL":"https:\/\/doi.org\/10.1002\/lary.25442","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,24]]}}}