{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T17:46:17Z","timestamp":1789753577229,"version":"4.0.1"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,7,7]],"date-time":"2015-07-07T00:00:00Z","timestamp":1436227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>This study explores whether changes in voice\u2010 and swallow\u2010related QoL are associated with progression of idiopathic Parkinson's disease (IPD). Furthermore, it examines the relationship between patients' perception of both voice and swallowing disorders in IPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective clinical study, quality of life (QoL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One\u2010hundred mentally competent IPD patients with voice and swallowing complaints were asked to answer four QoL questionnaires (Voice Handicap Index, MD Anderson Dysphagia Inventory, Visual Analog Scale [VAS] voice, and Dysphagia Severity Scale [DSS]). Differences in means for the QoL questionnaires and their subscales within Hoehn and Yahr stage groups were calculated using one\u2010way analysis of variance. The relationship between voice\u2010 and swallow\u2010related QoL questionnaires was determined with the Spearman correlation coefficient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Scores on both voice and swallow questionnaires suggest an overall decrease in QoL with progression of IPD. A plateau in QoL for VAS voice and the DSS was seen in the early Hoehn and Yahr stages. Finally, scores on voice\u2010related QoL questionnaires were significantly correlated with swallow\u2010related QoL outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Voice\u2010 and swallow\u2010related QoL decreases with progression of IPD. A significant association was found between voice\u2010 and swallow\u2010related QoL questionnaires. Healthcare professionals can benefit from voice\u2010 and swallow\u2010related QoL questionnaires in a multidimensional voice\u2010 or swallow\u2010assessment protocol. The patient's perception of his\/her voice and swallowing disorders and its impact on QoL in IPD should not be disregarded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2b <jats:italic>Laryngoscope<\/jats:italic>, 126:408\u2013414, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.25481","type":"journal-article","created":{"date-parts":[[2015,7,7]],"date-time":"2015-07-07T18:26:42Z","timestamp":1436293602000},"page":"408-414","source":"Crossref","is-referenced-by-count":50,"title":["Voice\u2010 and swallow\u2010related quality of life in idiopathic <scp>P<\/scp>arkinson's disease"],"prefix":"10.1002","volume":"126","author":[{"given":"Michel R. A.","family":"van Hooren","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Maastricht University Medical Center Maastricht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura W. 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