{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T19:35:19Z","timestamp":1788377719982,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,7,30]],"date-time":"2015-07-30T00:00:00Z","timestamp":1438214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To determine the safety and effectiveness of pediatric tympanoplasty performed on short\u2010term international medical missions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ethiopian children who had dry or nearly dry tympanic perforations and bilateral conductive hearing losses underwent postauricular tympanoplasties with underlain temporalis fascia grafts. Pre\u2010 and postoperative air and bone audiometry was performed. Complications, graft success, hearing improvement, and dry ear at 6\u2010month follow\u2010up were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients were 7 to 25 years old (24 female ears, 20 male ears). The majority had subtotal perforations. Operative findings included ossicular erosions and fixation by hypertrophic mucosa. There were no major medical complications or deaths in this series.<\/jats:p><jats:p>Of 44 ears, 27 had complete pre\u2010 and postoperative audiometric data. Twenty\u2010four of 44 surgeries resulted in an intact tympanic membrane. Twelve of 44 markedly reduced the perforation. Eight of 44 grafts failed. The mean improvement in PTA was 14 dB (range\u2009=\u2009\u22126\u201345 dB). Human immunodeficiency virus (HIV)+ patients had a high rate of graft failure (3\/4) and comprised 38% (3\/8) of complete graft failures (<jats:italic>P<\/jats:italic>\u2009=\u2009.015). Among the 20 ears with residual perforations, 14 were dry at 6\u2010month follow\u2010up. Of the six ears with drainage, three were HIV+ (<jats:italic>P<\/jats:italic>\u2009=\u2009.019).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pediatric tympanoplasty is a safe procedure in a short\u2010term surgical mission setting when high anesthetic and surgical standards are maintained. Surgical results were similar to those found in developing\u2010world university hospitals, but were worse than in United States or European series. HIV+ children did worse than their HIV\u2212\/unknown peers, with a high rate of graft failure and persistent otorrhea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4. <jats:italic>Laryngoscope<\/jats:italic>, 126:1464\u20131469, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.25486","type":"journal-article","created":{"date-parts":[[2015,7,30]],"date-time":"2015-07-30T14:15:13Z","timestamp":1438265713000},"page":"1464-1469","source":"Crossref","is-referenced-by-count":18,"title":["Results of pediatric tympanoplasty on short\u2010term surgical missions"],"prefix":"10.1002","volume":"126","author":[{"given":"Glenn","family":"Isaacson","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery"},{"name":"Department of Pediatrics Temple University School of Medicine Philadelphia Pennsylvania 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