{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T11:44:57Z","timestamp":1789472697617,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T00:00:00Z","timestamp":1446768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Objective\/Hypothesis<\/jats:title><jats:p>To describe clinically relevant between\u2010group differences in MD Anderson Dysphagia Inventory (MDADI) scores among head and neck cancer (HNC) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective cross\u2010sectional study was conducted in 1,136 HNC patients seen for modified barium swallow (MBS) studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The MDADI was administered by written questionnaire at the MBS appointment. MD Anderson Dysphagia Inventory global, composite, and subscale scores were calculated. Anchor\u2010based methods were employed to determine clinically meaningful between\u2010group differences by feeding tube status, aspiration status (per MBS study), and diet level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean MDADI scores for the 1,136 patients were: emotional 65.8\u2009\u00b1\u200917.3, functional 68.1\u2009\u00b1\u200919.6, physical 60.1\u2009\u00b1\u200918.6, global 59.3\u2009\u00b1\u200928.3, and composite 64.0\u2009\u00b1\u200917.1. Three hundred seventy\u2010eight patients (33%) were feeding tube\u2010dependent; 395 (34.8%) were aspirators; 122 (11%) were nothing per oral (Performance Status Scale\u2010Head and Neck [PSS\u2010HN] diet\u2009=\u20090); and 249 (22%) ate unrestricted, regular diets (PSS\u2010HN diet\u2009=\u2009100). Statistically significant (<jats:italic>P<\/jats:italic> &lt; 0.0001) between\u2010group differences (feeding tube vs. no feeding tube, aspirator vs. nonaspirator, oral vs. nonoral diet, PSS\u2010HN diet levels) were observed for all mean MDADI scores (global, composite, and subscales). A mean difference of 10 points in composite MDADI scores differentiated feeding tube\u2010dependent from nontube\u2010dependent patients, aspirators from nonaspirators, and distinct PSS\u2010HN diet levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We identify that a 10\u2010point between\u2010group difference in composite MDADI scores was associated with clinically meaningful between\u2010group differences in swallowing function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4. <jats:italic>Laryngoscope<\/jats:italic>, 126:1108\u20131113, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.25778","type":"journal-article","created":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T09:44:48Z","timestamp":1446803088000},"page":"1108-1113","source":"Crossref","is-referenced-by-count":163,"title":["What is a clinically relevant difference in <scp>MDADI<\/scp> scores between groups of head and neck cancer patients?"],"prefix":"10.1002","volume":"126","author":[{"given":"Katherine A.","family":"Hutcheson","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas, MD Anderson Cancer Center Houston Texas U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha P.","family":"Barrow","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas, MD Anderson Cancer Center Houston Texas U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asher","family":"Lisec","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas, MD Anderson Cancer Center Houston Texas U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise A.","family":"Barringer","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas, MD Anderson Cancer Center Houston Texas U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kacie","family":"Gries","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas, MD Anderson Cancer Center Houston Texas U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan S.","family":"Lewin","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas, MD Anderson Cancer Center Houston Texas U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,6]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"97","article-title":"Adaptation and validation of the Italian MD Anderson Dysphagia Inventory (MDADI)","volume":"129","author":"Schindler A","year":"2008","journal-title":"Rev Laryngol Otol Rhinol 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