{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T08:34:58Z","timestamp":1789893298271,"version":"4.0.1"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,3,12]],"date-time":"2016-03-12T00:00:00Z","timestamp":1457740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>The performance of an ossicular replacement prosthesis (ORP) is influenced by its alignment and appropriate tension between the tympanic membrane and the stapes footplate. A novel ORP with a flexible element that potentially allows for length adjustment in situ is presented and tested for acoustic performance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Laser Doppler vibrometry in fresh human cadaveric temporal bones was used to test the acoustic performance of the adjustable ORP relative to standard prostheses used for ossiculoplasty.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The three\u2010dimensional (3D) velocity of the stapes posterior crus was measured in the 0.2\u2010 to 20\u2010kHz range using a Polytec CLV\u20103D laser Doppler vibrometer. The middle ear cavity was accessed through a facial recess approach. After measuring the normal response, the incus was removed and stapes velocity was measured in the disarticulated case, then after insertion of the new prosthesis, a conventional prosthesis (Kurz BELL Dusseldorf type), and a sculpted autologous incus prosthesis in each temporal bone. The 3D stapes velocity transfer function (SVTF) was calculated for each case and compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The novel ORP design restored stapes velocity to within 6 dB (on average) of the intact response. No significant differences in 3D\u2010SVTF were found between the new, conventional, or autologous ORPs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The inclusion of an in situ adjustable element into the ORP design did not adversely affect its acoustic performance. The adjustable element may increase the ease of achieving optimal ORP placement, especially through a facial recess approach.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>NA <jats:italic>Laryngoscope<\/jats:italic>, 126:2559\u20132564, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.25901","type":"journal-article","created":{"date-parts":[[2016,3,14]],"date-time":"2016-03-14T05:38:22Z","timestamp":1457933902000},"page":"2559-2564","source":"Crossref","is-referenced-by-count":21,"title":["First results of a novel adjustable\u2010length ossicular reconstruction prosthesis in temporal bones"],"prefix":"10.1002","volume":"126","author":[{"given":"Peter K.","family":"Gottlieb","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering Stanford University Stanford California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiping","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Beijing Anzhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashkan","family":"Monfared","sequence":"additional","affiliation":[{"name":"Department of Otology and Neurotology George Washington University Hospital Washington District of Columbia U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolas","family":"Blevins","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Stanford University Stanford California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Puria","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering Stanford University Stanford California U.S.A."},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Stanford University Stanford California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200103000-00005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-6591-1_9"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200411000-00008"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200402000-00024"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004050050047"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000178151.44505.1b"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000169788.07460.4a"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480410018250"},{"key":"e_1_2_6_10_1","first-page":"233","article-title":"Hearing Research; 2010. 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