{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T17:40:59Z","timestamp":1695490859238},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,4,14]],"date-time":"2016-04-14T00:00:00Z","timestamp":1460592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2017,3]]},"abstract":"Objectives\/Hypothesis<\/jats:title>This study is a pilot study evaluating the feasibility of sampling nose blood during an emergency using a commercially available rapid test device. It also compares the accuracy of rapid nasal blood test results to the results of standard laboratory methods using venous blood sampling.<\/jats:p><\/jats:sec>Methods<\/jats:title>Nose blood was collected in patients suffering from active epistaxis. In an emergency setting, hemoglobin levels and the international normalized ratio (INR) were assessed using a rapid point\u2010of\u2010care test device. These results were compared to standard laboratory analyses from venous blood taken at the same time from the same patient. Twenty patients consented to and participated in these assessments.<\/jats:p><\/jats:sec>Results<\/jats:title>Linear regression comparing venous and nasal samples revealed strong correlations between the two methods for both hemoglobin and INR measurement. A Bland\u2010Altman analysis showed the mean difference to be 2.3 g\/L when comparing hemoglobin measurements made using the rapid point\u2010of\u2010care device to hemoglobin measurements made using conventional lab assessment. The corresponding mean difference for INR measurements was 0.14.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The results of this pilot study support the use of point\u2010of\u2010care test devices using nasal blood sampling and provide preliminary data demonstrating that a rapid testing method can be reliable, practicable, and time\u2010efficient. In our opinion, rapid hematologic screening for nasal and capillary blood should be available in emergency wards that treat epistaxis.<\/jats:p><\/jats:sec>Level of Evidence<\/jats:title>4. Laryngoscope<\/jats:italic>, 127:577\u2013581, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.26002","type":"journal-article","created":{"date-parts":[[2016,4,14]],"date-time":"2016-04-14T05:13:00Z","timestamp":1460610780000},"page":"577-581","source":"Crossref","is-referenced-by-count":1,"title":["A prospective pilot study comparing nasal blood sampling and venipuncture for the assessment of hemoglobin levels and INR"],"prefix":"10.1002","volume":"127","author":[{"given":"Rafael R.","family":"Stadler","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University Hospital Zurich USZ, University of Zurich UZH Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael B.","family":"Soyka","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery University Hospital Zurich USZ, University of Zurich UZH Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2013.5220"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2014.09.009"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12024"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.06.009"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000195369.01289.9B"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-010-1243-x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1916-0216-42-4"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.08.054"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.2500\/ar.2013.4.0049"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2012.04636.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aet252"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12118"},{"key":"e_1_2_7_15_1","article-title":"Comparison of the INR values measured by CoaguChek XS Coagulometer and conventional laboratory methods in patients on VKA therapy","author":"Kalcik M","year":"2015","journal-title":"Clin Appl Thromb Hemost"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.26002","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.26002","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.26002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T17:00:10Z","timestamp":1695488410000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.26002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,14]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1002\/lary.26002"],"URL":"https:\/\/doi.org\/10.1002\/lary.26002","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,14]]}}}