{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T18:54:06Z","timestamp":1726080846637},"reference-count":17,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,8,17]],"date-time":"2016-08-17T00:00:00Z","timestamp":1471392000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To evaluate clinical indications and endoscopic findings for patients undergoing transnasal esophagoscopy (TNE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective, multi\u2010institutional, observational cohort study at four tertiary centers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Demographics, reflux finding score, reflux symptom index, Eating Assessment Tool (EAT\u201010) scores, clinical indications, and endoscopic findings were compared among patients whose TNE findings resulted in a changes in management (FCIM), defined as a referral, new medication, or surgery recommendation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 329 patients who were enrolled nine (3%) were unable to complete the exam. In an adjusted regression model, male gender and elevated body mass index were significantly predictive of a positive TNE (<jats:italic>P<\/jats:italic> =.013\u2010.045); 51% (n = 162\/319) had TNE with FCIM. Common FCIM were esophageal stricture (7.5%), irregular Z\u2010line (27.4%), reflux esophagitis (12.8%), and infectious esophagitis (6.3%) (<jats:italic>P<\/jats:italic> &lt;.001\u2010.010). Overall, the average EAT\u201010 was higher for patients with FCIM (9.7 vs. 5.4) than in those without it (<jats:italic>P<\/jats:italic> =.014). Patients with a history of head and neck cancer (HNCA) had FCIM 64% of the time, which rose to 81% if they had both HNCA and dysphagia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In treatment\u2010seeking patients TNE is predictive of a change in management in males and obese patients. In patients with HNCA and dysphagia, TNE is likely to yield findings that cause a change in management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>2b. <jats:italic>Laryngoscope<\/jats:italic>, 126:2667\u20132671, 2016<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.26171","type":"journal-article","created":{"date-parts":[[2016,8,17]],"date-time":"2016-08-17T09:36:53Z","timestamp":1471426613000},"page":"2667-2671","source":"Crossref","is-referenced-by-count":10,"title":["Prospective multi\u2010institutional transnasal esophagoscopy: Predictors of a change in management"],"prefix":"10.1002","volume":"126","author":[{"given":"Rebecca J.","family":"Howell","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Cincinnati College of Medicine Cincinnati Ohio U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariah B.","family":"Pate","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery and Center for Voice Airway and Swallowing Georgia Regents University Augusta Georgia U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey L.","family":"Ishman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Cincinnati College of Medicine, and Divisions of Otolaryngology\u2013Head and Neck Surgery and Pulmonary Medicine, Cincinnati Children's Hospital Medical Center Cincinnati Ohio U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tova F.","family":"Isseroff","sequence":"additional","affiliation":[{"name":"New York Eye and Ear Infirmary of Mount Sinai New York New York U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam D.","family":"Rubin","sequence":"additional","affiliation":[{"name":"Lakeshore Professional Voice St. Clair Shores Michigan U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed M.","family":"Soliman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Lewis Katz School of Medicine at Temple University Philadelphia Pennsylvania U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory N.","family":"Postma","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery and Center for Voice Airway and Swallowing Georgia Regents University Augusta Georgia U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Pitman","sequence":"additional","affiliation":[{"name":"Voice and Swallowing Institute, Department of Otolaryngology\u2013Head and Neck Surgery, Columbia University Medical Center New York New York 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