{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:36:47Z","timestamp":1787063807739,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,8,31]],"date-time":"2016-08-31T00:00:00Z","timestamp":1472601600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Few studies report outcomes of surgical management of postinflammatory medial canal fibrosis (PIMCF). The objectives were to compare short\u2010 and long\u2010term outcomes after surgical repair of PIMCF at our institution and systematically aggregate published data for meta\u2010analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>Medical records for the case series; PubMed, Scopus, and OVID\/Medline for the systematic review\/meta\u2010analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients undergoing surgical treatment of PIMCF were identified. Short\u2010term (&lt;2 years) and long\u2010term (&gt;2 years) postoperative outcomes were evaluated for the case series and aggregated for the meta\u2010analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At our institution, 16 patients (21 ears) were identified. Compared to the preoperative air\u2010bone gap (ABG) (27.7 \u00b1 7.5 dB), mean postoperative short\u2010term ABG (8.2 \u00b1 7.5 dB) and long\u2010term ABG (15.3 \u00b1 11.3 dB) were significantly improved (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001 for both). Although short\u2010term restenosis rate was low (0%) among long\u2010term follow\u2010up patients, 64% (9 of 14) experienced some degree of recurrent canal narrowing, including one case of complete restenosis (7%). Similarly, meta\u2010analysis pooled preoperative ABG (29.3 \u00b1 9.7 dB, 95% confidence interval [CI] 27.0\u201331.6) improved significantly during short\u2010term (11.4 \u00b1 8.0 dB, 95% CI 8.3\u20134.5,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.0001) and long\u2010term (14.3 \u00b1 9.6 dB, 95% CI 11.6\u201316.9,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.0004) follow\u2010ups, with partial deterioration in hearing over time. Long\u2010term complete restenosis rate (13.8%) was worse than short\u2010term (8.0%), with no significant difference over time (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.85).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Postinflammatory medial canal fibrosis is a rare condition that can successfully be treated with surgery to restore patency of the external auditory canal. Patients who experience improved hearing early on, however, are at significant risk of restenosis and recurrence of their conductive hearing loss with time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      N\/A.\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 2016 127:488\u2013495, 2017\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.26214","type":"journal-article","created":{"date-parts":[[2016,8,31]],"date-time":"2016-08-31T02:40:34Z","timestamp":1472611234000},"page":"488-495","source":"Crossref","is-referenced-by-count":11,"title":["Postinflammatory medial canal fibrosis: An institutional review and meta\u2010analysis of short\u2010 and long\u2010term outcomes"],"prefix":"10.1002","volume":"127","author":[{"given":"Robert G.","family":"Keller","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Medical University of South Carolina Charleston South Carolina U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian A.","family":"Ong","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Medical University of South Carolina Charleston South Carolina U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaun A.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Medical University of South Carolina Charleston South Carolina U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan P.","family":"O'Connell","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Vanderbilt University Medical Center Nashville Tennessee U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul R.","family":"Lambert","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Medical University of South Carolina Charleston South Carolina U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,31]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1097\/MAO.0000000000000317","article-title":"Acquired atresia of the external auditory canal: long\u2010term clinical and audiometric results after surgery","volume":"35","author":"Dhooge I","year":"2014","journal-title":"Otol Neurotol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1993.01880140044007"},{"key":"e_1_2_6_4_1","first-page":"2","article-title":"Medial canal stenosis\u2014chronic stenosing external otitis","volume":"17","author":"Birman 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