{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T05:15:57Z","timestamp":1716959757048},"reference-count":10,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T00:00:00Z","timestamp":1481241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>Therapeutic monocolonal antibodies (MAbs) are a new, rapidly growing class of medications that frequently have poorly characterized side\u2010effect profiles. We present a patient who developed inflammatory lesions of the vocal folds in temporal relation to the initiation of alirocumab. Lesions of the vocal folds represent a previously unreported adverse effect of alirocumab therapy, making it the second MAb documented with such a side effect. The potential laryngeal effects of alirocumab specifically, and of MAbs more broadly, warrant investigation. <jats:italic>Laryngoscope<\/jats:italic>, 127:1652\u20131654, 2017<\/jats:p>","DOI":"10.1002\/lary.26426","type":"journal-article","created":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T09:37:10Z","timestamp":1481276230000},"page":"1652-1654","source":"Crossref","is-referenced-by-count":4,"title":["Association of alirocumab therapy with inflammatory lesions of the vocal folds: A case report"],"prefix":"10.1002","volume":"127","author":[{"given":"Peter A.","family":"Benedict","sequence":"first","affiliation":[{"name":"NYU Voice Center Department of Otolaryngology\u2013Head and Neck Surgery, New York University School of Medicine New York New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rania M.","family":"Abdou","sequence":"additional","affiliation":[{"name":"Phoniatrics Unit Department of Otorhinolaryngology, Alexandria University School of Medicine Alexandria Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory R.","family":"Dion","sequence":"additional","affiliation":[{"name":"NYU Voice Center Department of Otolaryngology\u2013Head and Neck Surgery, New York University School of Medicine New York New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peak","family":"Woo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Icahn School of Medicine New York New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan C.","family":"Branski","sequence":"additional","affiliation":[{"name":"NYU Voice Center Department of Otolaryngology\u2013Head and Neck Surgery, New York University School of Medicine New York New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milan R.","family":"Amin","sequence":"additional","affiliation":[{"name":"NYU Voice Center Department of Otolaryngology\u2013Head and Neck Surgery, New York University School of Medicine New York New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,12,9]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(01)00856-7"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-016-1364-1"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2014.09.001"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40259-016-0181-6"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hemonc.2014.06.003"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr515"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2014.1766"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2014.932348"},{"key":"e_1_2_5_10_1","unstructured":"Regeneron Pharmaceuticals Inc.Highlights of Praluent Prescribing Information. July 1 2015. Available at:http:\/\/www.regeneron.com\/Praluent\/Praluent\u2010fpi.pdf. Accessed August 2 2016."},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2016.00021"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.26426","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flary.26426","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.26426","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T06:07:49Z","timestamp":1696572469000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.26426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,9]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1002\/lary.26426"],"URL":"https:\/\/doi.org\/10.1002\/lary.26426","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,9]]}}}