{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T06:26:17Z","timestamp":1775543177730,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,9,22]],"date-time":"2017-09-22T00:00:00Z","timestamp":1506038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003766","name":"Ministry of Education","doi-asserted-by":"publisher","award":["2015R1D1A1A02062228"],"award-info":[{"award-number":["2015R1D1A1A02062228"]}],"id":[{"id":"10.13039\/501100003766","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008005","name":"Yonsei University College of Medicine","doi-asserted-by":"publisher","award":["6\u20102011\u20100122"],"award-info":[{"award-number":["6\u20102011\u20100122"]}],"id":[{"id":"10.13039\/501100008005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:sec><jats:title>Objectives\/Hypothesis<\/jats:title><jats:p>To evaluate the potential efficacy of steroid\u2010soaked, absorbable calcium alginate nasal packing following endoscopic sinus surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective, randomized, single\u2010blinded, placebo\u2010controlled trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010two patients (44 nostrils) who had chronic rhinosinusitis with polyps underwent bilateral endoscopic sinus surgery. Only those with an intersinus difference in Lund\u2010Mackay severity score of 1 or less were included. In each patient, one randomly selected nostril was packed with calcium alginate soaked with 2\u2009mL of triamcinolone (40\u2009mg\/mL) (triamcinolone group), whereas the contralateral nostril received an identical packing soaked in 2\u2009mL of normal saline (saline group). Two independent investigators blinded to the packing allocation scored the surgical field using the validated Perioperative Sinus Endoscopy (POSE) scores 1, 4, and 8 weeks after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All 44 nostrils were analyzed; the Lund\u2010Mackay scores did not differ significantly between the groups before surgery. Eight weeks after surgery, the total POSE scores were significantly lower in the triamcinolone group (<jats:italic>P<\/jats:italic>\u2009=\u2009.014). The POSE scoring parameters were then compared between groups, and the following variables were significantly different: middle turbinate synechiae with the lateral wall (<jats:italic>P<\/jats:italic>\u2009=\u2009.037), polypoid degeneration of the ethmoid cavity (<jats:italic>P<\/jats:italic>\u2009=\u2009.006), and sphenoid sinus severity (<jats:italic>P<\/jats:italic>\u2009=\u2009.036).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study demonstrated that steroid\u2010soaked, absorbable nasal packing can be used to enhance wound healing after endoscopic sinus surgery and to prevent polypoid changes in the nasal mucosa.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>1b. <jats:italic>Laryngoscope<\/jats:italic>, 128:311\u2013316, 2018<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.26871","type":"journal-article","created":{"date-parts":[[2017,9,22]],"date-time":"2017-09-22T06:16:44Z","timestamp":1506061004000},"page":"311-316","source":"Crossref","is-referenced-by-count":24,"title":["Randomized controlled trial of steroid\u2010soaked absorbable calcium alginate nasal packing following endoscopic sinus surgery"],"prefix":"10.1002","volume":"128","author":[{"given":"Chi Sang","family":"Hwang","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salma Saud","family":"Al Sharhan","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Imam Abdulrahman Bin Faisal University and King Fahd Hospital Dammam Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo Ra","family":"Kim","sequence":"additional","affiliation":[{"name":"Research Center for Human Natural 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